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anti-Hamster CTNNB1 antibody for Immunoprecipitation

Recommended CTNNB1 Antibody (supplied by: Log in to see )

Antigen
Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
  • armadillo
  • beta-catenin
  • Bfc
  • Catnb
  • CHBCAT
  • CTNNB
  • ctnnb
  • CTNNB1
  • ctnnb1
  • id:ibd2058
  • Jup
  • LOC100217813
  • Mesc
  • MRD19
  • wu:fb73e10
  • wu:fi81c06
  • wu:fk25h01
Reactivity
Hamster, Human, Mouse (Murine)
445
108
96
28
21
13
13
6
5
4
3
2
1
1
1
Host
Mouse
316
153
2
2
Clonality
Monoclonal
Conjugate
This CTNNB1 antibody is un-conjugated
15
12
9
6
6
6
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
402
153
116
99
83
65
65
32
16
13
8
4
3
3
2
1
1
1
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Catalog No. ABIN614788
$ 308.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089235755 ABIN457419 ICC FACS IP WB Mouse IgG1 C-Term, AA 441-448 Log in to see EM-22 3
0.00089235755 ABIN1723571 ICC FACS IHC (p) IP WB Mouse IgG1 Log in to see EM-22

Top referenced anti-CTNNB1 antibody for Immunoprecipitation

Similar anti-CTNNB1 Antibodies

Application / Reactivity Mouse (Murine) Human
Chromatin Immunoprecipitation (ChIP) 2 Antibodies 3 Antibodies
ELISA 25 Antibodies 145 Antibodies
Enzyme Immunoassay (EIA) 11 Antibodies 13 Antibodies
Flow Cytometry (FACS) 9 Antibodies 65 Antibodies
Immunocytochemistry (ICC) 9 Antibodies
Immunofluorescence (IF) 26 Antibodies
Immunohistochemistry (IHC) 35 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 31 Antibodies
Immunoprecipitation (IP) 18 Antibodies
Western Blotting (WB) 100 Antibodies
ELISA (Capture) 1 Antibodies

General

Antigen Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) Antibodies
Reactivity Hamster, Human, Mouse (Murine)
(445), (108), (96), (28), (21), (13), (13), (6), (5), (4), (3), (2), (1), (1), (1)
Host Mouse
(316), (153), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CTNNB1 antibody is un-conjugated
(15), (12), (9), (6), (6), (6), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(402), (153), (116), (99), (83), (65), (65), (32), (16), (13), (8), (4), (3), (3), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CTNNB1 Antibody

Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN614788) Images
Specificity This antibody reacts with C-terminal part of beta-Catenin, an 88 kDa multifunctional protein involved both in cell adhesion and in activation of transcription.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Hamster.
Species reactivity (tested):Human.
Purification Protein-A Affinity Chromatography
Immunogen Recombinant human beta-catenin
Clone EM-22
Isotype IgG1

Target Details CTNNB1

Product Details anti-CTNNB1 Antibody Application Details Handling References for anti-CTNNB1 Antibody (ABIN614788) Images back to top
Antigen
Alternative Name Catenin beta-1 (CTNNB1 Antibody Abstract)
Background Beta-catenin is a multifunctional protein involved both in cell adhesion and in activation of transcription. Calcium-dependent intercellular adhesion transmembrane glycoprotein E-cadherin interacts by its cytoplasmic domain with reciprocally bound alpha, beta and gamma catenin. Beta-catenin links this complex through alpha-actinin to the cytoskeleton. Functional cadherin-catenin system is important for invasiveness of tumour cells. Beta-catenin level in cytoplasm is controlled by glycogen synthase kinase-3 beta. When activity of this kinase is blocked (e.g. by excessive stimulation of Wnt signaling pathway), hypophosphorylated stable form of beta-catenin accumulates in the cytoplasm, translocates to the nucleus and activates transcription of genes including those that are involved in cell cycle control. As a result, cell division and neoplastic transformation are promoted.Synonyms: Beta-catenin, CTNNB, CTNNB1
Gene ID 1499
NCBI Accession NP_001091679
UniProt P35222
Research Area Signaling
Pathways WNT Signaling

Application Details

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Handling References for anti-CTNNB1 Antibody (ABIN614788) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details References for anti-CTNNB1 Antibody (ABIN614788) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH ~7.4, 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-CTNNB1 Antibody (ABIN614788)

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling Images back to top
Background publications

Nowak, Madej, Dziegiel: "Expression of E-cadherin, beta-catenin and Ki-67 antigen and their reciprocal relationships in mammary adenocarcinomas in bitches." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 45, Issue 3, pp. 233-8, 2007

Jung, Chung, Kim, Kim, Heo, Ahn, Hwang, Kim, Lee, Kim, Kim, Chang: "Epstein-Barr virus, beta-catenin, and E-cadherin in gastric carcinomas." in: Journal of Korean medical science, Vol. 22, Issue 5, pp. 855-61, 2007

Valenta, Lukas, Korinek: "HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells." in: Nucleic acids research, Vol. 31, Issue 9, pp. 2369-80, 2003

Images

Product Details anti-CTNNB1 Antibody Target Details CTNNB1 Application Details Handling References for anti-CTNNB1 Antibody (ABIN614788) back to top
Supplier Images
Immunofluorescence (IF) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (ABIN614788) anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
Western Blotting (WB) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (ABIN614788) anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (Image 2)
Flow Cytometry (FACS) image for anti-CTNNB1 antibody (Catenin (Cadherin-Associated Protein), beta 1, 88kDa) (ABIN614788) anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody (Image 3)