anti-Dog (Canine) DKK1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended DKK1 Antibody (supplied by: Log in to see )

Antigen
Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies
  • dkk
  • dkk-1
  • xdkk1
  • Xdkk-1
  • Dickkopf1
  • dickkopf-1
  • dkk1
  • mdkk-1
  • DKK-1
  • SK
  • dkk1-A
  • CT34
  • SGY
  • SGY-1
  • SGY1
  • AI414495
  • Soggy
  • mSgy
  • dickkopf 1 homolog (Xenopus laevis)
  • dickkopf WNT signaling pathway inhibitor 1
  • dickkopf protein
  • dickkopf 1b
  • dickkopf homolog 1 (Xenopus laevis)
  • dickkopf-like 1
  • DKK1
  • dkk1
  • dickkopf
  • dkk1b
  • Dkk1
  • DKKL1
  • Dkkl1
Epitope
AA 207-247
35
26
14
12
11
9
8
8
6
6
6
5
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
204
55
49
24
9
9
8
7
5
4
4
4
3
3
2
2
1
1
1
Host
Rabbit
155
41
21
2
1
Clonality
Polyclonal
Conjugate
This DKK1 antibody is un-conjugated
9
7
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
159
98
40
34
12
6
5
4
3
2
1
1
1
1
1
1
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Catalog No. ABIN678158
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.569705 ABIN296913 IHC (p) ELISA WB Goat AA 250-262 Log in to see Polyclonal
1 ABIN1733668 IHC (p) ELISA WB Goat C-Term Log in to see Polyclonal
1 ABIN678167 IHC (p) WB HRP Rabbit IgG AA 207-247 Log in to see Polyclonal
1 ABIN678160 IHC (p) WB Biotin Rabbit IgG AA 207-247 Log in to see Polyclonal

General

Antigen Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies
Epitope AA 207-247
(35), (26), (14), (12), (11), (9), (8), (8), (6), (6), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(204), (55), (49), (24), (9), (9), (8), (7), (5), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(155), (41), (21), (2), (1)
Clonality
Polyclonal
Conjugate This DKK1 antibody is un-conjugated
(9), (7), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(159), (98), (40), (34), (12), (6), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-DKK1 Antibody

Target Details DKK1 Application Details Handling ProductDetails: References for anti-DKK1 antibody (ABIN678158) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human DKK1
Isotype IgG

Target Details DKK1

Product Details anti-DKK1 Antibody Application Details Handling ProductDetails: References for anti-DKK1 antibody (ABIN678158) Images back to top
Antigen
Alternative Name Dkk1 (DKK1 Antibody Abstract)
Background

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Subcellular location: Secreted

Synonyms: SK, DKK-1, Dickkopf-related protein 1, Dickkopf-1, hDkk-1, DKK1, UNQ492/PRO18

Gene ID 22943
UniProt O94907
Research Area Embryogenesis, Wnt
Pathways WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-DKK1 Antibody Target Details DKK1 Handling ProductDetails: References for anti-DKK1 antibody (ABIN678158) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-DKK1 Antibody Target Details DKK1 Application Details ProductDetails: References for anti-DKK1 antibody (ABIN678158) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-DKK1 antibody (ABIN678158)

Product Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling Images back to top
Product cited in:

Lu, Duan, Zhang, Wu, Wang: "Expression of Wnt3a, Wnt10b, ?-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." in: Acta odontologica Scandinavica, pp. 1-7, 2015

Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, 2014

Images

Product Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling ProductDetails: References for anti-DKK1 antibody (ABIN678158) back to top
Supplier Images
Western Blotting (WB) image for anti-Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) (AA 207-247) antibody (ABIN678158) Image kindly provided by Dr. Magdalena Krol. Control tumor cells, tumor cells grown i...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) (AA 207-247) antibody (ABIN678158) Image kindly submitted by Dr. Magdalena Krol. Formalin-fixed and paraffin embedded ca...