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Browse our IGFBP4 Proteins (IGFBP4)

Full name:
Insulin-Like Growth Factor Binding Protein 4 Proteins (IGFBP4)
On www.antibodies-online.com are 36 Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) Proteins from 14 different suppliers available. Additionally we are shipping IGFBP4 Antibodies (232) and IGFBP4 Kits (70) and many more products for this protein. A total of 348 IGFBP4 products are currently listed.
Synonyms:
AI875747, BP-4, Deb2, HT29-IGFBP, IBP-4, IBP4, IGF-BP4, IGFBP-4, igfbp4
list all proteins Gene Name GeneID UniProt
IGFBP4 3487 P22692
IGFBP4 16010 P47879
IGFBP4 360622 P21744

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IGFBP4 Proteins (IGFBP4) by Origin

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Top referenced IGFBP4 Proteins

  1. Mouse (Murine) IGFBP4 Protein expressed in HEK-293 - ABIN2666963 : Bunn, Fowlkes: Insulin-like growth factor binding protein proteolysis. in Trends in endocrinology and metabolism: TEM 2003 (PubMed)
    Show all 5 references for ABIN2666963

  2. Mouse (Murine) IGFBP4 Protein expressed in Human Cells - ABIN2007569 : Durai, Davies, Yang, Yang, Seifalian, Goldspink, Winslet: Biology of insulin-like growth factor binding protein-4 and its role in cancer (review). in International journal of oncology 2006 (PubMed)
    Show all 4 references for ABIN2007569

  3. Human IGFBP4 Protein expressed in Human Cells - ABIN2003660 : Sitar, Popowicz, Siwanowicz, Huber, Holak: Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 4 references for ABIN2003660

  4. Cynomolgus IGFBP4 Protein expressed in Human Cells - ABIN2009804 : Zhou, Diehl, Hoeflich, Lahm, Wolf: IGF-binding protein-4: biochemical characteristics and functional consequences. in The Journal of endocrinology 2003 (PubMed)
    Show all 3 references for ABIN2009804

More Proteins for IGFBP4 Interaction Partners

Human Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) interaction partners

  1. Data show that insulin-like growth factor binding protein-4 (IGFBP-4) was significantly elevated in lupus nephritis, particularly those with renal pathology chronicity changes.

  2. The present study provides the first evidence that apoptosis inhibitor of macrophages binds to IGFBP2, 3 and 4.

  3. Data show that co-transfection with cDNA encoding stanniocalcin-1 (show STC1 Proteins) abrogates the proteolytic activity of pregnancy-associated plasma protein-A (PAPP-A (show PAPPA Proteins)) toward IGF-binding protein 4 (IGFBP-4).

  4. PLasma IGFBP-4 levels are not acutely altered following myocardial infarction treated with heparin and percutaneous coronary intervention.

  5. High IGFBP-4 fragment levels were associated with increased all-cause and cardiovascular mortality rates in T1D patients with and without diabetic nephropathy.

  6. Data indicate co-localization of insulin (show INS Proteins)-like growth factor binding proteins IGFBP-4, IGFBP-5 (show IGFBP5 Proteins) in the syncytiotrophoblast layer of first trimester placental villi as early as 5 weeks of gestational age.

  7. IGF-1 (show IGF1 Proteins)/IGFbp4 signaling regulated the post-developmental adipose tissue expansion.

  8. Despite the relation of CT-IGFBP4 to a more severe coronary artery disease, CT- and NT-IGFBP4, in contrast to our report based on total PAPP-A (show PAPPA Proteins), failed to predict any long-term outcomes in patients with stable cardiovascular disease.

  9. these findings demonstrate an oncogenic property for IBP (show TSPO Proteins) in promoting the metastatic potential of breast cancer cells.

  10. PAPP-A (show PAPPA Proteins) and IGFBP-4 gene expression (microarray analysis) was significantly upregulated in IL-1beta (show IL1B Proteins)- or TNF-alpha (show TNF Proteins)-exposed cells.

Mouse (Murine) Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) interaction partners

  1. exerts a negative effect on basal intestinal growth but plays a positive regulatory role in the intestinotropic actions of GLP-2

  2. IGF-1 (show IGF1 Proteins)/IGFbp4 signaling regulated the post-developmental adipose tissue expansion.

  3. Igfbp2-5 are expressed in distinct and complementary patterns during cochlear development.

  4. SOX9 (show SOX9 Proteins) is a transcriptional regulator of IGFBP-4 and that SOX9 (show SOX9 Proteins)-induced activation of IGFBP-4 may be one of the mechanisms by which SOX9 (show SOX9 Proteins) suppresses cell proliferation and progression of colon cancer.

  5. findings indicate that the defect in p53 function and the increased proteolysis of IGFBP-4, we had observed, represent two components of the same pathway, which contributes to the oncogenic function of Skp2B

  6. Inactivation of IGFBP4 diminished the anabolic effects of PAPP-A (show PAPPA Proteins) on bone.

  7. Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice

  8. IGFBP-4 is a potential growth inhibitor of lymphoid tissues.

  9. This study demonstrates that ES of muscle cells in vitro not only directly modulates the gene expression of contractile proteins but also modulates proteins that are part of the IGF regulatory system, in particular IGFBP-4.

  10. Crystallization, heparin and IGF binding (show HTRA1 Proteins), and osteogenic activity of IGFBP4 in its native conformation

Cow (Bovine) Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) interaction partners

  1. IGFBP4 maternal blood concentrations were lower during pregnancy than during non-pregnant cycles and synchronized control cycles. The lower IGFBP4 in maternal blood may result in an increase of free insulin (show INS Proteins)-like growth factor- for local action.

  2. follicular dominance was associated with low or decreased follicular fluid concentrations of IGFBP-4 and -5

Pig (Porcine) Insulin-Like Growth Factor Binding Protein 4 (IGFBP4) interaction partners

  1. Sequence analysis showed that the porcine IBP4 gene encodes a protein of 259 amino acids which shares high homology with the insulin-like growth factor binding protein 4 (IBP4) of eight species.

IGFBP4 Protein Profile

Protein Summary

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Alternative names and synonyms associated with IGFBP4

  • insulin-like growth factor binding protein 4 (IGFBP4)
  • insulin-like growth factor binding protein 4 (igfbp4)
  • insulin-like growth factor binding protein 4 (LOC100194498)
  • insulin-like growth factor binding protein 4 (LOC100225608)
  • insulin-like growth factor binding protein 4 (LOC100271886)
  • insulin-like growth factor binding protein 4 (Igfbp4)
  • insulin-like growth factor binding protein 4 (LOC100337926)
  • AI875747 protein
  • BP-4 protein
  • Deb2 protein
  • HT29-IGFBP protein
  • IBP-4 protein
  • IBP4 protein
  • IGF-BP4 protein
  • IGFBP-4 protein
  • igfbp4 protein

Protein level used designations for IGFBP4

insulin-like growth factor binding protein 4 , IBP-4 , IGF-binding protein 4 , insulin-like growth factor-binding protein 4 , Band 3A , differentially expressed in B16F10 2 , IGFBP-4 , insulin-like growth factor binding protein-4 , IBP4

GENE ID SPECIES
454652 Pan troglodytes
700963 Macaca mulatta
100136305 Oncorhynchus mykiss
100194498 Salmo salar
100225608 Taeniopygia guttata
100271886 Takifugu rubripes
3487 Homo sapiens
16010 Mus musculus
360622 Rattus norvegicus
282262 Bos taurus
374271 Gallus gallus
608158 Canis lupus familiaris
100144490 Sus scrofa
100860812 Capra hircus
100337926 Oryctolagus cuniculus
100730717 Cavia porcellus
443470 Ovis aries
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