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IGFBP4 Protein (AA 22-258) (His tag)

IGFBP4 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1096870
  • Target See all IGFBP4 Proteins
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-258
    Origin
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Source
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This IGFBP4 protein is labelled with His tag.
    Purpose
    Recombinant Human Insulin-Like Growth Factor-Binding Protein 4/IGFBP-4 (C-6His)
    Sequence
    DEAIHCPPCS EEKLARCRPP VGCEELVREP GCGCCATCAL GLGMPCGVYT PRCGSGLRCY PPRGVEKPLH TLMHGQGVCM ELAEIEAIQE SLQPSDKDEG DHPNNSFSPC SAHDRRCLQK HFAKIRDRST SGGKMKVNGA PREDARPVPQ GSCQSELHRA LERLAASQSR THEDLYIIPI PNCDRNGNFH PKQCHPALDG QRGKCWCVDR KTGVKLPGGL EPKGELDCHQ LADSFREVDH HHHHH
    Characteristics
    Recombinant Human Insulin-Like Growth Factor-Binding Protein 4/IGFBP-4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (D22-E258) of Human IGFBP4 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product IGFBP4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))
    Alternative Name
    igfbp-4 (IGFBP4 Products)
    Synonyms
    IGFBP4 Protein, igfbp4 Protein, BP-4 Protein, HT29-IGFBP Protein, IBP4 Protein, IGFBP-4 Protein, AI875747 Protein, Deb2 Protein, IGF-BP4 Protein, IBP-4 Protein, insulin like growth factor binding protein 4 Protein, insulin-like growth factor-binding protein 4 Protein, insulin-like growth factor binding protein 4 Protein, IGFBP4 Protein, LOC100136305 Protein, LOC100194498 Protein, igfbp4 Protein, Igfbp4 Protein
    Sub Type
    Fusionprotein
    Background
    IGFBP-4, whose full name is insulin-like growth factor-binding protein 4, is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain, and can bind IGF2. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.
    Alternative Names: Insulin-Like Growth Factor-Binding Protein 4, IBP-4, IGF-Binding Protein 4, IGFBP-4, IGFBP4, IBP4
    Molecular Weight
    27.01 kDa
    UniProt
    P22692
    Pathways
    WNT Signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process
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