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|Application / Reactivity||Human||Rat (Rattus)|
|Immunofluorescence (fixed cells) (IF/ICC)||1 Antibodies||1 Antibodies|
|Western Blotting (WB)||57 Antibodies||12 Antibodies|
|Neutralization (Neut)||2 Antibodies|
|Immunostaining (ISt)||1 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||10 Antibodies||3 Antibodies|
|Immunohistochemistry (IHC)||7 Antibodies||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||13 Antibodies||13 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies||1 Antibodies|
|Immunoassay (IA)||1 Antibodies|
|Flow Cytometry (FACS)||4 Antibodies|
|Antigen||Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) Antibodies|
|Epitope||AA 189-205, Middle Region Alternatives|
|Reactivity||Human, Rat (Rattus) Alternatives|
|Conjugate||This IGFBP6 antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-IGFBP6 AntibodyTarget Details IGFBP6 Application Details Handling Images
Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 6(IGFBP6) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: insulin-like growth factor binding protein 6
Protein Name: Insulin-like growth factor-binding protein 6(IBP-6/IGF-binding protein 6/IGFBP-6)
|Purification||Immunogen affinity purified.|
|Immunogen||A synthetic peptide corresponding to a sequence in the middle region of human IGFBP6(189-205aa NCDHRGFYRKRQCRSSQ), different from the related rat sequence by two amino acids.|
Target Details IGFBP6Product Details anti-IGFBP6 Antibody Application Details Handling Images back to top
|Alternative Name||IGFBP6 (IGFBP6 Antibody Abstract)|
|Background||Insulin-like growth factor-binding protein 6(IGFBP6) is a protein that in humans is encoded by the IGFBP6 gene. The IGFBP6 gene is mapped to chromosome 12. In all, it has contained 216 amino acid protein with a calculated molecular mass of 22,847 Da. Kato et al.(1995) showed that the human keratinocyte cell line HaCat secretes IGFBP6 as an autocrine growth inhibitor. Recombinant IGFBP6 was also shown to inhibit growth of HaCat cells and other keratinocyte cell lines.|
|Research Area||Signaling, Diabetes, Metabolism, Growth Factors|
|Pathways||WNT Signaling, Myometrial Relaxation and Contraction|
Application DetailsProduct Details anti-IGFBP6 Antibody Target Details IGFBP6 Handling Images back to top
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IGFBP6 Antibody Target Details IGFBP6 Application Details Images back to top
|Reconstitution||Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.|
|Buffer||Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.|
|Preservative||Thimerosal (Merthiolate), Sodium azide|
|Precaution of Use||This product contains Thimerosal (Merthiolate),Sodium azide a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||-20 °C,4 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
|Expiry Date||12 months|
ImagesProduct Details anti-IGFBP6 Antibody Target Details IGFBP6 Application Details Handling back to top