|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||2 Antibodies|
|Immunohistochemistry (IHC)||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||1 Antibodies|
|Western Blotting (WB)||20 Antibodies|
|Antigen||Lethal Giant Larvae Homolog 1 (Drosophila) (LLGL1) Antibodies|
|Conjugate||This LLGL1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|3 references available|
|Supplier||Log in to see|
Product Details anti-LLGL1 AntibodyTarget Details LLGL1 Application Details Handling References for anti-LLGL1 Antibody (ABIN357635) Images
|Specificity||This antibody is specific to LLGL1 (N-term). Predicted to cross react with Mouse (100 % Antigen Homology).|
|Purification||Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LLGL1.|
Target Details LLGL1Product Details anti-LLGL1 Antibody Application Details Handling References for anti-LLGL1 Antibody (ABIN357635) Images back to top
|Alternative Name||LLGL1 (LLGL1 Antibody Abstract)|
|Background||LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17.Synonyms: DLG4, HUGL, HUGL1, Hugl-1, Human homolog to the D-lgl gene protein, LLGL, LLGL1, Lethal(2) giant larvae protein homolog 1|
|Molecular Weight||114379 Da|
|Gene ID||3996, 9606|
Application DetailsProduct Details anti-LLGL1 Antibody Target Details LLGL1 Handling References for anti-LLGL1 Antibody (ABIN357635) Images back to top
ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-LLGL1 Antibody Target Details LLGL1 Application Details References for anti-LLGL1 Antibody (ABIN357635) Images back to top
|Buffer||PBS with 0.09 % (W/V) Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-LLGL1 Antibody (ABIN357635)Product Details anti-LLGL1 Antibody Target Details LLGL1 Application Details Handling Images back to top
Schimanski, Schmitz, Kashyap et al.: "Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer." in: Oncogene, Vol. 24, Issue 19, pp. 3100-9, 2005 (PubMed).
Grifoni, Garoia, Schimanski et al.: "The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo." in: Oncogene, Vol. 23, Issue 53, pp. 8688-94, 2004 (PubMed).
Katoh, Katoh: "Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico." in: International journal of oncology, Vol. 24, Issue 3, pp. 737-42, 2004 (PubMed).
ImagesProduct Details anti-LLGL1 Antibody Target Details LLGL1 Application Details Handling References for anti-LLGL1 Antibody (ABIN357635) back to top