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Browse our anti-LRP5 (LRP5) Antibodies

Full name:
anti-Low Density Lipoprotein Receptor-Related Protein 5 Antibodies (LRP5)
On www.antibodies-online.com are 119 Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies from 18 different suppliers available. Additionally we are shipping LRP5 Proteins (9) and LRP5 Kits (8) and many more products for this protein. A total of 140 LRP5 products are currently listed.
Synonyms:
BMND1, EVR1, EVR4, HBM, LR3, LRP5, lrp5-A, LRP6, LRP7, mKIAA4142, OPPG, OPS, OPTA1, VBCH2, Xlrp5
list all antibodies Gene Name GeneID UniProt
LRP5 4041 O75197
LRP5 16973 Q91VN0
LRP5 293649  

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Top referenced anti-LRP5 Antibodies

  1. Human Polyclonal LRP5 Primary Antibody for EIA, WB - ABIN953209 : Abramowitz, Muntner, Coco, Southern, Lotwin, Hostetter, Melamed: Serum alkaline phosphatase and phosphate and risk of mortality and hospitalization. in Clinical journal of the American Society of Nephrology : CJASN 2010 (PubMed)
    Show all 4 references for ABIN953209

  2. Human Monoclonal LRP5 Primary Antibody for FACS, ELISA - ABIN969535 : Urano, Shiraki, Usui, Sasaki, Ouchi, Inoue: A1330V variant of the low-density lipoprotein receptor-related protein 5 (LRP5) gene decreases Wnt signaling and affects the total body bone mineral density in Japanese women. in Endocrine journal 2009 (PubMed)
    Show all 2 references for ABIN969535

  3. Human Polyclonal LRP5 Primary Antibody for WB - ABIN127323 : Del Valle-Pérez, Arqués, Vinyoles, de Herreros, Duñach: Coordinated action of CK1 isoforms in canonical Wnt signaling. in Molecular and cellular biology 2011 (PubMed)
    Show all 2 references for ABIN127323

  4. Human Polyclonal LRP5 Primary Antibody for IHC, ELISA - ABIN185410 : He, Semenov, Tamai, Zeng: LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. in Development (Cambridge, England) 2004 (PubMed)
    Show all 2 references for ABIN185410

  5. Human Monoclonal LRP5 Primary Antibody for ELISA, WB - ABIN517568 : Kim, Goel, Alexander: Differentiation generates paracrine cell pairs that maintain basaloid mouse mammary tumors: proof of concept. in PLoS ONE 2011 (PubMed)

More Antibodies against LRP5 Interaction Partners

Xenopus laevis Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) interaction partners

  1. The extracellular domains of Lrp5/6 behave as physiologically relevant inhibitors of noncanonical Wnt (show WNT2 Antibodies) signaling during Xenopus and mouse development in vivo.

Zebrafish Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) interaction partners

  1. Data show that in zebrafish, lrp5 also controls cell migration during early morphogenetic processes and contributes to shaping the craniofacial skeleton.

Human Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) interaction partners

  1. Lrp5 controls glucose uptake and growth of MDA-MB-231 human breast cancer cells.

  2. Data show that LDL receptor (show LDLR Antibodies)-related protein 5 (show CAPS Antibodies) (LRP5) gain-of-function mutations do not activate beta-catenin (show CTNNB1 Antibodies) signaling in osteoblasts.

  3. findings suggest that rescuing LRP5/6-mediated Wnt (show WNT2 Antibodies) signaling improves neuronal cell survival and reduces tau phosphorylation, which support the hypothesis that Wnt (show WNT2 Antibodies) signaling might be an attractive therapeutic strategy for managing AD

  4. Molecular testing identified biallelic lipoprotein receptor-related protein (show LRP1 Antibodies) 5 (show CAPS Antibodies) (LRP5) mutations (NM_002335.3:c. [889dupA]; [2827 + 1G > A]) confirming a diagnosis of osteoporosis-pseudoglioma (OPPG) syndrome.

  5. Lrp5 binds to Frizzled, preventing Frz-regulated non-canonical Wnt (show WNT2 Antibodies) pathway activation and further non-canonical pathway-mediated tumour metastasis.

  6. Reciprocally, a low bone mineral density-associated common LRP5 allele correlated with increased abdominal adiposity.

  7. No mutations in LRP5 and LRP6 (show LRP6 Antibodies) could be identified

  8. This is the first study to suggest the genetic influence of LRP5 A1330V polymorphism on bone mineral density in COPD (show ARCN1 Antibodies) patients, independent of the development of emphysema.

  9. Although AFFs have been reported in other rare bone diseases, this is the first in a genetic condition of primary osteoblast dysfunction. The relatively low bone turnover observed, and knowledge of LRP5 function

  10. No LRP5 variant was found to be associated with type 2 diabetes mellitus in Han Chinese, but haplotype TT was found to be associated with type 2 diabetes mellitus .

Mouse (Murine) Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) interaction partners

  1. LRP5 function in mice causes retinal hypovascularization during development as well as retinal neovascularization in adulthood with disorganized and leaky vessels.

  2. Lrp5 is required for glucose uptake, and glucose uptake regulates the growth rate of mammary epithelial cells in culture.

  3. Data show that LDL receptor (show LDLR Antibodies)-related protein 5 (show CAPS Antibodies) (LRP5) gain-of-function mutations do not activate beta-catenin (show CTNNB1 Antibodies) signaling in osteoblasts.

  4. These in vivo data support in vitro studies regarding the mechanism of HBM-causing mutations, and imply that HBM LRP5 receptors differ in their relative sensitivity to inhibition by SOST (show SOST Antibodies) and DKK1 (show DKK1 Antibodies).

  5. Lrp5 A214V and G171V were partially or fully protected from the bone loss that normally results frommechanical disuse using two models, tail suspension and Botulinum toxin-induced muscle paralysis, in two different Lrp5 HBM knock-in mouse models.

  6. In hypercholesterolemia LRP5(-/-) mice Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway was shut down. An antiatherogenic role for LRP5 was demonstrated as HC LRP5(-/-) mice developed larger aortic atherosclerotic lesions than WT mice.

  7. Report accelerated lung regeneration by platelet-rich plasma extract through Lrp5/Tie2 (show TEK Antibodies) pathway.

  8. Data show that low density lipoprotein receptor-related protein 5 (LRP5) and the canonical Wnt (show WNT2 Antibodies) pathway down-regulation regulate the dyslipidaemic profile by promoting lipid and macrophage retention in the vessel wall.

  9. Lrp5 binds to Frizzled, preventing Frz-regulated non-canonical Wnt (show WNT2 Antibodies) pathway activation and further non-canonical pathway-mediated tumour metastasis.

  10. Sclerostin (show SOST Antibodies) inhibits bone formation through Lrp5 interaction.

LRP5 Antigen Profile

Antigen Summary

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Alternative names and synonyms associated with LRP5

  • low density lipoprotein receptor-related protein 5 (LRP5) antibody
  • low density lipoprotein receptor-related protein 5 (lrp5) antibody
  • low density lipoprotein receptor-related protein 5 (LOC100220027) antibody
  • low density lipoprotein receptor-related protein 5 (Lrp5) antibody
  • BMND1 antibody
  • EVR1 antibody
  • EVR4 antibody
  • HBM antibody
  • LR3 antibody
  • LRP5 antibody
  • lrp5-A antibody
  • LRP6 antibody
  • LRP7 antibody
  • mKIAA4142 antibody
  • OPPG antibody
  • OPS antibody
  • OPTA1 antibody
  • VBCH2 antibody
  • Xlrp5 antibody

Protein level used designations for LRP5

Lipoprotein Receptor Related Protein 5 , low density lipoprotein receptor-related protein 5 , low-density lipoprotein receptor-related protein 5 , low-density lipoprotein receptor-related protein 5-like , LRP-5 , low density lipoprotein receptor-related protein 7 , LRP-7 , low-density lipoprotein receptor-related protein 7

GENE ID SPECIES
100147353 Equus caballus
100009566 Oryctolagus cuniculus
373722 Xenopus laevis
451380 Pan troglodytes
568518 Danio rerio
100189542 Papio anubis
100220027 Taeniopygia guttata
100406268 Callithrix jacchus
100473379 Ailuropoda melanoleuca
100491803 Xenopus (Silurana) tropicalis
100548748 Meleagris gallopavo
4041 Homo sapiens
16973 Mus musculus
293649 Rattus norvegicus
423114 Gallus gallus
100306933 Canis lupus familiaris
534450 Bos taurus
100524299 Sus scrofa
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