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AASS Products

(Aminoadipate Semialdehyde Synthase (AASS))

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This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008].

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Featured AASS Categories

AASS Antibodies

High quality antibodies with extensive validation data.

AASS Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AASS Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7444178
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7143840
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN389270
Quantity 400 μL
Datasheet Datasheet

Recommended AASS Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088404
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136940
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417786
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AASS products

Houten, Te Brinke, Denis, Ruiter, Knegt, de Klerk, Augoustides-Savvopoulou, Häberle, Baumgartner, Coşkun, Zschocke, Sass, Poll-The, Wanders, Duran: "Genetic basis of hyperlysinemia." in: Orphanet journal of rare diseases, Vol. 8, pp. 57, (2013) (PubMed).

Synonyms and alternative names related to AASS

aminoadipate-semialdehyde synthase (AASS), aminoadipate-semialdehyde synthase (Aass), LKR, LKR/SDH, LKRSDH, LOR, LOR/SDH, LORSDH, Lorsdh, SDH

Protein level used designations for AASS

  • alpha-aminoadipate semialdehyde synthase
  • alpha-aminoadipic semialdehyde synthase, mitochondrial
  • aminoadipic semialdehyde synthase
  • lysine-2-oxoglutarate reductase
  • lysine-ketoglutarate reductase /saccharopine dehydrogenase
  • lysine oxoglutarate reductase
  • saccharopine dehydrogenase
  • LKR/SDH
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