anti-CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) Antibodies

CTDSP1 encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. Additionally we are shipping CTDSP1 Proteins (7) and CTDSP1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CTDSP1 363249  
CTDSP1 58190 Q9GZU7
CTDSP1 227292 P58466
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Top anti-CTDSP1 Antibodies at antibodies-online.com

Showing 10 out of 108 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CTDSP1 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell CTDSP1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Goat Un-conjugated ELISA, IHC   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Goat Un-conjugated ELISA, IHC, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of CTDSP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CTDSP1 expression in Jurkat (A), HuvEc (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CTDSP1 Antibody (N-term) in Jurkat cell line lysates (35ug/lane). This demonstrates the CTDSP1 antibody detected the CTDSP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$515.63
Details
Human Goat Biotin ELISA, IHC, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa/HuvEc cells, using CTDSP1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

Top referenced anti-CTDSP1 Antibodies

  1. Human Polyclonal CTDSP1 Primary Antibody for IHC (p), ELISA - ABIN545075 : Yeo, Lin, Dahmus, Gill: A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 Pubmed References

  2. Dog (Canine) Polyclonal CTDSP1 Primary Antibody for ELISA - ABIN451599 : Zhang, Kim, Genoud, Gao, Kelly, Pfaff, Gill, Dixon, Noel: Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. in Molecular cell 2006 (PubMed)

More Antibodies against CTDSP1 Interaction Partners

Human CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) interaction partners

  1. Our results provide a novel mechanistic insight into the activation of Myc by 27-HC via transcriptional repression of PP2A, SCP1 and FBW7 to increase Myc protein stability in breast cancer cells.

  2. SCP1 is the phosphatase that counterregulates the MAPK-mediated phosphorylation of Ser(68)-Twist1.

  3. SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Serine-62.

  4. hSCP1 may be an beta-O-linked N-acetylglucosamine modified protein in vivo.

  5. CTDSP1 activity stabilizes REST in stem cells and ERK-dependent phosphorylation combined with Pin1 activity promotes REST degradation in neural progenitors.

  6. SCP1 phosphatase substrate specificity: CdcA3 could be an enzymatic substrate for SCP1.

  7. Captured the phosphoryl-aspartate intermediate in the crystal structure of a Scp1D206A mutant soaked with para-nitrophenyl phosphate (pNPP), providing strong evidence for the proposed mechanism.

  8. Polymorphisms vary significantly between races; Not associated with TB susceptibility in Caucasians.

  9. SCP1 may play a role in the regulation of gene expression, possibly by controlling the transition from initiation/capping to processive transcript elongation

  10. results show that REST/NRSF recruits SCPs to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells

  11. SCP1 acts as a phosphatase for regulatory phosphorylations in the linker region of Smad1 and Smad2.

Mouse (Murine) CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1) interaction partners

  1. Consistently, the authors observed increased AKT phosphorylation and angiogenesis followed by enhanced tumorigenesis in Ctdsp1 (which encodes SCP1) gene - knockout mice. Importantly, they discovered that the membrane localization of SCP1 is crucial for impeding angiogenesis and tumor growth, and this localization depends on palmitoylation of a conserved cysteine motif within its NH2 terminus.

  2. Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas PKCalpha-phosphorylated BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP.

  3. Findings suggest that SCP1 may inhibit the osteoblastic differentiation induced by the BMP-Smad axis via Runx2 by suppressing downstream effector(s).

  4. Expression and purification of the active variant of recombinant murine Golli-interacting protein (GIP) and its characterization

CTDSP1 Antigen Profile

Protein Summary

This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with CTDSP1

  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1) antibody
  • CTD small phosphatase 1 (CTDSP1) antibody
  • CTD small phosphatase 1 (Ctdsp1) antibody
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (ctdsp1) antibody
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (HCAG_04820) antibody
  • carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTRG_06220) antibody
  • CTD small phosphatase 1 (ctdsp1) antibody
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (Ctdsp1) antibody
  • CTDSP1 antibody
  • fj83f12 antibody
  • GIP antibody
  • im:7141428 antibody
  • Nif3 antibody
  • NLI-IF antibody
  • NLIIF antibody
  • SCP1 antibody
  • wu:fj83f12 antibody
  • zgc:113169 antibody

Protein level used designations for CTDSP1

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 , CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 , NLI-interacting factor 3 , nuclear LIM interactor-interacting factor 3 , small C-terminal domain phosphatase 1 , golli-interacting protein , small CTD phosphatase 1

GENE ID SPECIES
608466 Canis lupus familiaris
516199 Bos taurus
459943 Pan troglodytes
363249 Rattus norvegicus
58190 Homo sapiens
553744 Danio rerio
5447218 Ajellomyces capsulatus NAm1
8301559 Candida tropicalis MYA-3404
100350904 Oryctolagus cuniculus
100380164 Xenopus (Silurana) tropicalis
227292 Mus musculus
100726065 Cavia porcellus
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