anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Non-Specific Cross Reacting Antigen) (CEACAM6) Antibodies

Carcinoembryonic antigen (CEA\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. Additionally we are shipping CEACAM6 Proteins (11) and CEACAM6 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CEACAM6 100125369  
CEACAM6 4680 P40199
CEACAM6    
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Top anti-CEACAM6 Antibodies at antibodies-online.com

Showing 10 out of 112 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated cELISA, FACS, IHC (fro), ELISA, WB Specificity testing of 9A6. Members of the CEA family were expressed on BOSC cells after transient transfection with expression vectors containing either the cDNA of CEACAM1, 5, 6, 7 or 8. Recognition of CEACAM3 and 4 was tested on stably transfected HeLa cells (CEACAM4). Expression of the constructs was confirmed with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 5 and 6: 
D14HD11, CEACAM7: CAC2, CEACAM8: 80H3 (green curves). An irrelevant monoclonal antibody served as a negative control (black curves). For specificity testing, protein G-purified 9A6 was tested on all CEACAM transfectants. A positive signal was only obtainedwith CEACAM6-expressing cells (red curves). Reactivity of FITC-labelled GM-9A6 with polymorph nuclear cells. 2 x 105 polymorph nuclear cells (PMN) with (green) or without (blue) prior incubation with PMA were reacted for 30 min at 4°C with FITC conjugated GM-9A6 (40 ug/ml) or with an isotype match 100 μg Log in to see 6 to 7 Days
$466.13
Details
Guinea Pig Rabbit Un-conjugated WB WB Suggested Anti-CEACAM6 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-CEACAM6 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate Rabbit Anti-CEACAM6 Antibody  Paraffin Embedded Tissue: Human Lung Cellular Data: Alveolar cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
$249.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD66c expression in HEK293T (A), NS-1 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 100 μg Log in to see 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse APC FACS Detection of CEACAM-6/CD66c in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CEACAM-6/CD66c APC-conjugated Monoclonal Antibody. Detection of CEACAM-6/CD66c in HEK293 Human Cell Line Transfected with Human CEACAM-6/CD66c and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human CEACAM-6/CD66c or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human CEACAM-6/CD66c APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$428.27
Details
Human Rabbit FITC FACS Profile of anti-CEACAM6 (CD66c) reactivity on SK-BR3 cells analyzed by flow cytometry. 50 Tests Log in to see 14 to 16 Days
$223.24
Details
Human Mouse Un-conjugated EIA, FACS, IHC (fro), WB   0.1 mg Log in to see 10 to 12 Days
$687.04
Details
Human Mouse Un-conjugated ELISA, FACS Flow cytometric analysis of Human CEACAM6 expression on human whole blood granulocytes. Cells were stained with purified anti-Human CEACAM6, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. 100 μg Log in to see 14 to 16 Days
$247.82
Details

Top referenced anti-CEACAM6 Antibodies

  1. Human Monoclonal CEACAM6 Primary Antibody for EIA, FACS - ABIN5541783 : Kalina, Vaskova, Mejstrikova, Madzo, Trka, Stary, Hrusak: Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens. in BMC cancer 2005 (PubMed)
    Show all 10 Pubmed References

  2. Human Monoclonal CEACAM6 Primary Antibody for FACS - ABIN2689376 : Skubitz, Campbell, Ahmed, Skubitz: CD66 family members are associated with tyrosine kinase activity in human neutrophils. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal CEACAM6 Primary Antibody for FACS - ABIN4897481 : Gebauer, Wicklein, Tachezy, Grob, Steinemann, Manukjan, Göhring, Schlegelberger, Maar, Izbicki, Bockhorn, Schumacher: Establishment and Characterization of a Pair of Patient-derived Human Non-small Cell Lung Cancer Cell Lines from a Primary Tumor and Corresponding Lymph Node Metastasis. in Anticancer research 2016 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CEACAM6 Primary Antibody for cELISA, FACS - ABIN108733 : Daniel, Nagel, Johnson, Lobo, Hirn, Jantscheff, Kuroki, von Kleist, Grunert: Determination of the specificities of monoclonal antibodies recognizing members of the CEA family using a panel of transfectants. in International journal of cancer. Journal international du cancer 1993 (PubMed)
    Show all 25 Pubmed References

  5. Human Polyclonal CEACAM6 Primary Antibody for IHC, WB - ABIN2776853 : Muenzner, Rohde, Kneitz, Hauck: CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. in The Journal of cell biology 2005 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CEACAM6 Interaction Partners

Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Non-Specific Cross Reacting Antigen) (CEACAM6) interaction partners

  1. CEACAM6 promoted oral squamous cell carcinoma cell invasion, migration, cytoskeletal rearrangement, and metastasis via interaction with EGFR and enhancing it activation.

  2. Studies provide evidence that dysregulated overexpression of CEACAM6 plays a role in several of the hallmarks of cancer, including uncontrolled proliferation, anoikis resistance, immune evasion, invasion and metastasis. [review]

  3. Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3, CEACAM5 or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA into host cells.

  4. Here, the authors identify members of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1, CEACAM3, CEACAM5 and CEACAM6.

  5. CD66c (KOR-SA3544) antigen expression of leukemic blasts in pediatric acute myeloid leukemia with TLS/FUS-ERG fusion transcript

  6. Data suggest that the expression of these TSPAN8, LGALS4, COL1A2 and CEACAM6 in the whole blood may be useful in the detection of colorectal cancer (CRC).

  7. expression is increased in severe asthma and primarily associated with airway epithelial cells and tissue neutrophils

  8. a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO, CEACAM8, CRISP3, MS4A3, CEACAM6, HEMGN, and MMP8

  9. In enterocytic C2BBe1 cells, Candida albicans caused a transient tyrosine phosphorylation of CEACAM1 and induced higher expression of membrane-bound CEACAM1 and soluble CEACAM6.

  10. Monoclonal Antibody 1B5A5 Against CEACAM6

  11. western blot analysis results indicated that the 1B5A5 epitope is located within an amino-terminal domain of CEACAM6. These results raised the possibility that our approach could lead to discovery of novel biomarkers for the early stage of cancers in a relatively short period of time.

  12. show the upregulation of the tumor-associated antigens CEACAM5/6 by trans-signaling of the pro-inflammatory cytokine IL-6

  13. Biliary CEACAM6 can identify patients with extrahepatic cholangiocarcinoma with a high degree of sensitivity and should be investigated further as a potential screening tool.

  14. Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another.

  15. CEACAM6 protein and mRNA were increased ~4-fold in lungs from infants with chronic lung disease as compared with controls.

  16. vaccination with recombinant attenuated Salmonella harboring the CEACAM6 and 4-1BBL gene efficiently increased the number of CD3+CD8+ TIL and NK cells, decreased the number of FOXP3 cells and inhibited the development of DMH-induced colorectal cancer

  17. CEACAM6 increased the levels of phosphorylated AKT, which is involved in the progression of a variety of human tumors.

  18. Data show that carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) and forkhead box P3 (FOXP3) are associated with the malignant degree of pancreatic cancer.

  19. Data indicate that carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes angiogenesis in gastric cancer via focal adhesion kinase FAK signaling.

  20. Results show that pancreatic cancer patients with CEACAM 1, 5 and 6 expression showed a significantly shortened overall survival and elevated serum values are correlated with distant metastasis suggesting a role in epithelial-mesenchymal transition.

CEACAM6 Antigen Profile

Protein Summary

Carcinoembryonic antigen (CEA\; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988

Gene names and symbols associated with CEACAM6

  • carcinoembryonic antigen-related cell adhesion molecule 6 (Ceacam6) antibody
  • carcinoembryonic antigen related cell adhesion molecule 6 (CEACAM6) antibody
  • CD66c antibody
  • CEAL antibody
  • NCA antibody

Protein level used designations for CEACAM6

carcinoembryonic antigen-related cell adhesion molecule 6 , non-specific crossreacting antigen , normal cross-reacting antigen

GENE ID SPECIES
100125369 Rattus norvegicus
4680 Homo sapiens
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