anti-Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA) Antibodies

The protein encoded by IL28RA belongs to the class II cytokine receptor family. Additionally we are shipping Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) Proteins (7) and Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL28RA 242700 Q8CGK5
IL28RA 163702 Q8IU57
IL28RA 362628  
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Top anti-Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-IL28RA Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Host:  Rabbit  Target Name:  IL28RA  Sample Tissue:  Human Fetal Lung  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-IL28RA Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of IL-28RA expression in HepG2 (A) whole cell lysates. 200 μL 13 to 14 Days
$487.50
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Cow Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$727.83
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Human Rabbit Un-conjugated ELISA, WB 100 μL Available
$363.46
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Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
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Human Rabbit Un-conjugated ELISA, WB Western blot analysis IL28RA using HeLa whole cell lysates 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human larynx labeled with Rabbit Anti-IL-28R Polyclonal Antibody, Unconjugated (ABIN1387718) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using IFNLR1 antibody. Western blot analysis of extracts of various cell lines, using IFNLR1 antibody (ABIN4904012) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. 100 μL 11 to 13 Days
$366.77
Details
Mouse Goat Un-conjugated FACS, IHC, ELISA   200 μg 11 to 14 Days
$713.17
Details

Top referenced anti-Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) Antibodies

  1. Human Polyclonal IL28RA Primary Antibody for CyTOF, FACS - ABIN4899570 : Wongthida, Diaz, Galivo, Kottke, Thompson, Pulido, Pavelko, Pease, Melcher, Vile: Type III IFN interleukin-28 mediates the antitumor efficacy of oncolytic virus VSV in immune-competent mouse models of cancer. in Cancer research 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal IL28RA Primary Antibody for ICC, IF - ABIN4325104 : Zahn, Rehkämper, Kümmerer, Ferring-Schmidt, Bieber, Tüting, Wenzel: Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus. in The Journal of investigative dermatology 2010 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal IL28RA Primary Antibody for WB - ABIN2783214 : Chae, Park, Li, Lee, Yang, Zhang, Kim, Chung: Analysis of the variations in IL-28RA gene and their association with allergic rhinitis. in Experimental & molecular medicine 2006 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal IL28RA Primary Antibody for FACS - ABIN4896336 : Yu, Wan, Cao, Zhang, Chen, Tan, Wang, Sun, Zhang, Wan, Zhu, Liu, Wu, Liu, Wu: Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action. in Scientific reports 2017 (PubMed)

More Antibodies against Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) Interaction Partners

Mouse (Murine) Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA) interaction partners

  1. Ifnlr1 is expressed in the epithelial fraction along the length of the gastrointestinal tract and is essential for induction of IFN-lambda-mediated sterilizing innate immunity to norovirus.

  2. interferon-lambda has a role in noncanonical signaling through IFNLR1, which tightens the blood-brain barrier and restricts viral neuroinvasion and pathogenesis

  3. Rotavirus infection induces production of IFN-lambda by IECs and of IL-22 by ILC3 cells.

  4. IL-28R is essential for optimal in vivo activity of natural killer cells

Human Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA) interaction partners

  1. Interferon lambda receptor 1 (IFNLR1) mRNA is increased in human rhinovirus (HRV) bronchiolitis infants. Increased IFNLR1 transcript levels characterized HRV-infected infants with more severe bronchiolitis and blood eosinophilia. IFNLR1 transcript is increased in infants infected with HRVC species.

  2. IFN-lambda4 suppressed HIV infection of macrophages. This IFN-lambda4-mediated HIV inhibition was compromised by the antibodies against IFN-lambda receptor complex, IFN-lambdaR1/IL-10R2.

  3. Significant associations were observed for 4 variants in IFNAR2, IFNLR1 with hepatitis B virus infection, and IFNLR1-rs4649203 was associated with hepatitis B recovery. Moreover, the authors demonstrated the clear relevance of 5 polymorphisms in IFNA1, IFNA2, IFNL4 with hepatocellular carcinoma.

  4. In this structure, the receptor peptide forms an 85-A-long extended chain, in which both the previously identified box1 and box2 regions bind simultaneously to the FERM and SH2-like domains of JAK1.

  5. Results show that IFNLR1 box1 and box2 motifs are required for stable complex formation with JAK1 and the crystal structure of JAK1 reveals IFNLR1 box1 binding site in the FERM domain. Also, structure-based mutagenesis reveals IFNLR1 PxxLxF motif that is essential for binding. Structure of JAK1 with IL10RA box1 indicates conservation among class II receptors.

  6. Selective expression of IFNlambdaR1 was considered to be a plus point towards the targeted anti-viral activity of IFNlambdas but artificial control on its expression will surely make IFNlambdas a better drug with enhanced activity.

  7. expression of IL-28RA mRNA may be correlated with the pathogenesis of systemic lupus erythematosus

  8. Polymorphism within the IL-28R1, but not in IL-28B, is associated with benign prostatic hyperplasia and lower urinary tract symptoms in Chinese.

  9. Results show that the distribution of IL10RB and IL28RA genotypes among the Hepatitis C virus-infected and control groups did not differ significantly.

  10. This study is the first to show the activation of a type III interferon response in low-risk human papillomavirus positive cervical cells and suggests that the lack of this response may be related to lesion progression.

  11. IL28RA polymorphism (rs10903035) seems to be implicated in the glucose homeostasis because AA genotype increases the likelihood of IR, but this association was different depending on hepatic fibrosis and HCV genotype.

  12. Epigenetic reprogramming of IFNLR1-mediated response potentiates antiviral activity and suppresses tumor growth.

  13. IFN-lambda receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-lambda3 genotype and with nonresponsiveness to IFN-alpha therapies.

  14. The rs12980275 AG/GG genotype and rs10903035 G allele remained independently associated with early pegylated interferon and ribavirin failure of hepatitis C in hepatitis C/HIV coinfected patients.

  15. Plasmacytoid dendritic cells are major producers of IFN-lambda2 (a type III interferon) in response to viral stimulation and also express functional receptors for this cytokine.

  16. No consistent association is found between IL28RA and multiple sclerosis in a Basque-Spanish population.

  17. two SNPs in IL28RA are correlated with susceptibility to HCV infection and spontaneous viral clearance, which implicates a primary role of IL28RA in the outcomes of HCV infection

  18. IFN-lambdaR1 consists of two distinct domains having fibronectin type III topology.

  19. Although the IFN-lambda1(Bac)-IFN-lambda1R1 and IFN-lambda1(Ins)-IFN-lambda1R1 complexes differed only in the nature of the expression system used for the ligand, their crystallization conditions and crystal forms were quite different

  20. study supports that IFN-lambdas do not influence every type of cell and that membrane-associated variant IFN-lambda R1 expression is not sufficient to ensure cellular sensitivity toward these cytokines.

Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene names and symbols associated with IL28RA

  • interferon lambda receptor 1 (IFNLR1) antibody
  • interferon, lambda receptor 1 (ifnlr1) antibody
  • interferon, lambda receptor 1 L homeolog (ifnlr1.L) antibody
  • interferon lambda receptor 1 (Ifnlr1) antibody
  • interferon, lambda receptor 1 (Ifnlr1) antibody
  • CRF2-12 antibody
  • CRF2/12 antibody
  • IFNLR antibody
  • ifnlr1 antibody
  • IL-28R1 antibody
  • Il28ra antibody
  • LICR2 antibody
  • RGD1562689 antibody

Protein level used designations for IL28RA

interferon lambda receptor isotype 1 , interferon lambda receptor soluble 1 , interleukin 28 receptor, alpha (interferon, lambda receptor) , interferon lambda receptor , interleukin-28 receptor subunit alpha-like , IFN-lambda R1 , IL-28 receptor subunit alpha , IL-28R-alpha , IL-28RA , class II cytokine receptor 12 , cytokine receptor class-II member 12 , cytokine receptor family 2 member 12 , interferon-lambda receptor 1 , interleukin 28 receptor alpha , interleukin-28 receptor subunit alpha , CRF2-12 , IFN-lambda receptor 1 , IFN-lambda-R1 , class II cytokine receptor CRF2/12 , interferon lambda receptor 1 , interferon lambda, receptor 1 , interleukin 28 alpha receptor , interleukin 28 receptor A , interleukin or cytokine receptor 2 , likely interleukin or cytokine receptor 2

GENE ID SPECIES
419694 Gallus gallus
456628 Pan troglodytes
612276 Canis lupus familiaris
100329166 Xenopus (Silurana) tropicalis
100381152 Xenopus laevis
100450173 Pongo abelii
100588530 Nomascus leucogenys
242700 Mus musculus
163702 Homo sapiens
362628 Rattus norvegicus
616826 Bos taurus
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