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IL28RA antibody (N-Term)

IL28RA Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2783214
  • Target See all IL28RA Antibodies
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    Binding Specificity
    • 16
    • 12
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 41
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig
    Host
    • 44
    • 1
    • 1
    Rabbit
    Clonality
    • 46
    Polyclonal
    Conjugate
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL28RA antibody is un-conjugated
    Application
    • 41
    • 23
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    EECAGTKELL CSMMCLKKQD LYNKFKGRVR TVSPSSKSPW VESEYLDYLF
    Predicted Reactivity
    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 77%, Rabbit: 86%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against IL28RA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human IL28RA
    Top Product
    Discover our top product IL28RA Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 491 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mucha, Majchrzak, Taciak, Hellmén, Król: "MDSCs mediate angiogenesis and predispose canine mammary tumor cells for metastasis via IL-28/IL-28RA (IFN-?) signaling." in: PLoS ONE, Vol. 9, Issue 7, pp. e103249, (2014) (PubMed).

  • Target
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    Alternative Name
    IL28RA (IL28RA Products)
    Synonyms
    IFNLR1 antibody, IL28RA antibody, crf2/12 antibody, ifnlr antibody, il-28r1 antibody, il28ra antibody, licr2 antibody, ifnlr1 antibody, CRF2-12 antibody, Il28ra antibody, CRF2/12 antibody, IFNLR antibody, IL-28R1 antibody, LICR2 antibody, RGD1562689 antibody, interferon lambda receptor 1 antibody, interferon, lambda receptor 1 antibody, interferon, lambda receptor 1 L homeolog antibody, IFNLR1 antibody, ifnlr1 antibody, ifnlr1.L antibody, Ifnlr1 antibody
    Background
    IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL-28R1, IL28RA
    Protein Interaction Partner: IFNLR1, IFNL1, IFNL2, LSM8,
    Protein Size: 491
    Molecular Weight
    54 kDa
    Gene ID
    163702
    NCBI Accession
    NM_173064, NP_775087
    UniProt
    Q5VTX8
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