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IL28RA Products

(Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Featured IL28RA Categories

IL28RA Antibodies

High quality antibodies with extensive validation data.

IL28RA ELISA Kits

Reliable ELISA kits for a wide range of species.

IL28RA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IL28RA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7156606
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6749738
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC
Validations
  • (1)
  • (1)
Cat. No. ABIN1387718
Quantity 100 μL
Datasheet Datasheet

Recommended IL28RA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883402
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385245
Quantity 96 tests
Datasheet Datasheet

Recommended IL28RA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307806
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3082005
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093116
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our IL28RA products

McGuire, Frieling, Lo, Li, Muhammad, Lawrence, Lawrence, Cook, Lynch: "Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer." in: Nature communications, Vol. 12, Issue 1, pp. 723, (2021) (PubMed).

Xia, Wolf, Vijayan, Studstill, Ma, Hahm: "Casein Kinase 1α Mediates the Degradation of Receptors for Type I and Type II Interferons Caused by Hemagglutinin of Influenza A Virus." in: Journal of virology, Vol. 92, Issue 7, (2018) (PubMed).

Yu, Wan, Cao, Zhang, Chen, Tan, Wang, Sun, Zhang, Wan, Zhu, Liu, Wu, Liu, Wu: "Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action." in: Scientific reports, Vol. 7, Issue 1, pp. 1729, (2017) (PubMed).

Saxena, Simon, Zeng, Blutt, Crawford, Sastri, Karandikar, Ajami, Zachos, Kovbasnjuk, Donowitz, Conner, Shaw, Estes: "A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 4, pp. E570-E579, (2017) (PubMed).

Apostolou, Kapsogeorgou, Konsta, Giotakis, Saridaki, Andreakos, Tzioufas: "Expression of type III interferons (IFNλs) and their receptor in Sjögren's syndrome." in: Clinical and experimental immunology, Vol. 186, Issue 3, pp. 304-312, (2016) (PubMed).

Mucha, Majchrzak, Taciak, Hellmén, Król: "MDSCs mediate angiogenesis and predispose canine mammary tumor cells for metastasis via IL-28/IL-28RA (IFN-?) signaling." in: PLoS ONE, Vol. 9, Issue 7, pp. e103249, (2014) (PubMed).

Magracheva, Pletnev, Kotenko, Li, Wlodawer, Zdanov: "Purification, crystallization and preliminary crystallographic studies of the complex of interferon-lambda1 with its receptor." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 66, Issue Pt 1, pp. 61-3, (2010) (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

Zahn, Rehkämper, Kümmerer, Ferring-Schmidt, Bieber, Tüting, Wenzel: "Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus." in: The Journal of investigative dermatology, Vol. 131, Issue 1, pp. 133-40, (2010) (PubMed).

Wongthida, Diaz, Galivo, Kottke, Thompson, Pulido, Pavelko, Pease, Melcher, Vile: "Type III IFN interleukin-28 mediates the antitumor efficacy of oncolytic virus VSV in immune-competent mouse models of cancer." in: Cancer research, Vol. 70, Issue 11, pp. 4539-49, (2010) (PubMed).

Synonyms and alternative names related to IL28RA

interferon lambda receptor 1 (IFNLR1), interferon, lambda receptor 1 (ifnlr1), interferon, lambda receptor 1 L homeolog (ifnlr1.L), interferon lambda receptor 1 (Ifnlr1), interferon, lambda receptor 1 (Ifnlr1), CRF2-12, crf2/12, CRF2/12, ifnlr, IFNLR, IFNLR1, ifnlr1, il-28r1, IL-28R1, IL28RA, il28ra, Il28ra, licr2, LICR2, RGD1562689

Protein level used designations for IL28RA

  • interferon lambda receptor isotype 1
  • interferon lambda receptor soluble 1
  • interleukin 28 receptor, alpha (interferon, lambda receptor)
  • interferon lambda receptor
  • interleukin-28 receptor subunit alpha-like
  • IFN-lambda R1
  • IL-28 receptor subunit alpha
  • IL-28R-alpha
  • IL-28RA
  • class II cytokine receptor 12
  • cytokine receptor class-II member 12
  • cytokine receptor family 2 member 12
  • interferon-lambda receptor 1
  • interleukin 28 receptor alpha
  • interleukin-28 receptor subunit alpha
  • CRF2-12
  • IFN-lambda receptor 1
  • IFN-lambda-R1
  • class II cytokine receptor CRF2/12
  • interferon lambda receptor 1
  • interferon lambda, receptor 1
  • interleukin 28 alpha receptor
  • interleukin 28 receptor A
  • interleukin or cytokine receptor 2
  • likely interleukin or cytokine receptor 2
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