SMURF2 Proteins
(SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3. In this way, SMAD2 may recruit substrates, such as SNON, for ubiquitin-mediated degradation. Enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2. Coexpression of SMURF2 with SMAD1 results in considerable decrease in steady-state level of SMAD1 protein and a smaller decrease of SMAD2 level (By similarity).
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| SMURF2 Protein (AA 1-748) (His tag) | Human | HEK-293 Cells |
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starts at $12,595.45
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| SMURF2 Protein (AA 1-748) (His tag) | Mouse | HEK-293 Cells |
|
starts at $12,595.45
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|
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| SMURF2 Protein (His tag) | Human | Escherichia coli (E. coli) |
|
$345.09
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|
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| SMURF2 Protein (GST tag) | Human | Baculovirus infected Insect Cells |
|
$919.38
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|
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| SMURF2 Protein (AA 1-748) (Strep Tag) | Human | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
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|
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| SMURF2 Protein (AA 1-748) (Strep Tag) | Mouse | Cell-free protein synthesis (CFPS) |
|
starts at $19,692.86
View price
|
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| SMURF2 Protein (AA 1-748, full length) (His tag) | Human | Yeast |
|
$544.50
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|
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| SMURF2 Protein (AA 1-748, full length) (GST tag) | Human | Escherichia coli (E. coli) |
|
$488.40
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|
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| SMURF2 Protein (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$956.40
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|
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| SMURF2 Protein (AA 246-400) (His tag) | Human | Bacteria |
|
$426.25
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|
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| SMURF2 Protein (His tag) | Human | Escherichia coli (E. coli) |
|
$478.00
View price
|
Protein
- PS (Protein Structure: Validation image available)
- Grade
- custom-made
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7555579
starts at
$12,595.45
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to:
United States
Delivery in 41 to 67 Business Days
Protein
- PS (Protein Structure: Validation image available)
- Grade
- custom-made
- Origin
- Mouse
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7561867
starts at
$12,595.45
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to:
United States
Delivery in 41 to 67 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7579604
$345.09
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 12 to 15 Business Days
Protein
- Origin
- Human
- Host
- Baculovirus infected Insect Cells
- Protein Type
- Recombinant
Catalog No. ABIN7857334
$919.38
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Grade
- custom-made
- Origin
- Human
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3095583
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Grade
- custom-made
- Origin
- Mouse
- Host
- Cell-free protein synthesis (CFPS)
- Protein Type
- Recombinant
- Purity
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3130681
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
250 μg
Shipping to:
United States
Delivery in 55 to 67 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- Origin
- Human
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN5714482
$544.50
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN5711831
$488.40
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2732271
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Catalog No. ABIN7818907
$426.25
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7945567
$478.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Aliases for SMURF2 Proteins
SMAD specific E3 ubiquitin protein ligase 2 (SMURF2) ProteinsSMAD specific E3 ubiquitin protein ligase 2 (smurf2) Proteins
SMAD specific E3 ubiquitin protein ligase 2 (Smurf2) Proteins
SMAD specific E3 ubiquitin protein ligase 2 S homeolog (smurf2.S) Proteins
2810411E22Rik Proteins
AI558114 Proteins
AI649275 Proteins
RGD1310067 Proteins
SMURF2 Proteins
wu:fb82a11 Proteins
wu:fc41c02 Proteins
Did you look for something else?
- SMURF1 Proteins
- SMUG1 Proteins
- SMU1 Proteins
- SMTNL1 Proteins
- SMS Proteins
- SMPX Proteins
- SMPDL3B Proteins
- SMPDL3A Proteins
- SMPD3 Proteins
- SMPD2 Proteins
- SMPD1 Proteins
- SMOX Proteins
- Smoothelin Proteins
- SMOC1 Proteins
- SMO Proteins
- SMNDC1 Proteins
- SMN2 Proteins
- SMN1 Proteins
- SMG9 Proteins
- SMG7 Proteins
- SMYD3 Proteins
- SMYD5 Proteins
- SNAI3 Proteins
- SNAIL Proteins
- SNAP23 Proteins
- SNAP29 Proteins
- SNAP47 Proteins
- SNAPC2 Proteins
- SNAPC3 Proteins
- SNAPC4 Proteins
- SNAPC5 Proteins
- SNAPIN Proteins
- SNCA Proteins
- SNCAIP Proteins
- SNCG Proteins
- SND1 Proteins
- SNF7 Proteins
- SNF8 Proteins
- SNIP1 Proteins
- SNRK Proteins
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