TIMP Metallopeptidase Inhibitor 1 Proteins (TIMP1)

TIMP1 belongs to the TIMP gene family. Additionally we are shipping TIMP1 Antibodies (317) and TIMP1 Kits (145) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TIMP1 7076 P01033
TIMP1 116510 P30120
TIMP1 21857 P12032
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Top TIMP1 Proteins at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Human Cells Human His tag 10 μg Log in to see 20 to 21 Days
$206.80
Details
HEK-293 Cells Human His tag 10 μg Log in to see 2 to 3 Days
$235.00
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Human Cells Mouse Un-conjugated 10 μg Log in to see 20 to 21 Days
$272.80
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Human Cells Rat Un-conjugated 10 μg Log in to see 20 to 21 Days
$272.80
Details
HEK-293 Cells Mouse Un-conjugated 10 μg Log in to see 10 to 12 Days
$226.22
Details
HEK-293 Cells Human His tag Validation with Western Blot 10 μg Log in to see 8 to 11 Days
$242.00
Details
HEK-293 Cells Mouse His tag Validation with Western Blot 10 μg Log in to see 8 to 11 Days
$242.00
Details
Human Human Un-conjugated 10 μg Log in to see 6 to 7 Days
$482.80
Details

TIMP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , ,
Rat (Rattus) , ,

Mouse (Murine) , , , , ,
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More Proteins for TIMP Metallopeptidase Inhibitor 1 (TIMP1) Interaction Partners

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. In dilation cardiomyopathy, expression of MMP-2 (show MMP2 Proteins), MMP-9 (show MMP9 Proteins), and TIMP-1 and their ratios in autopsy material and in cultures was elevated by 1.5-9 times.

  2. High Co-expression of TIMP-1 and CD63 (show CD63 Proteins) is associated with glioblastoma.

  3. plasma levels of TIMP-1 are associated with pancreatic lesion-induced cachexia in patients without jaundice.

  4. the expressions of TIMP1 can predict prognosis in astrocytic tumors

  5. It is well established by now that progression of melanoma depends on ECM (show MMRN1 Proteins) remodeling, TIMPs family being one of the most important regulators of this process.

  6. Authors observed a significant increase in the immunoexpression of collagen I and III in patients with DCM and a significant reduction in the immunoexpression of MMP-1 (show MMP1 Proteins) compared with the control group. Also, the collagen I and TIMP-1 expression indicated a positive linear correlation and respectively a negative linear relationship with collagen III and MMP-1 (show MMP1 Proteins).

  7. Low TIMP1 expression is associated with cervical cancer.

  8. In III-rd trimester of pregnancy parameters of Timp-1 and Survivin (show BIRC5 Proteins) - anti-apoptotic substances concentration were similar in maternal and cord blood in both artery and vein. We found no increased activity of selected antiapoptotic factors.

  9. Reduced expression of types I and III collagen and TIMP-1 as well as the increased expression of MMP-1 (show MMP1 Proteins) and MMP-8 (show MMP8 Proteins) in the anterior vaginal wall tissues play important roles in the onset of pelvic organ prolapse.

  10. no significant difference was detected in the expression level of individual MMP9 and TIMP1 genes in SCZ patients versus healthy controls either in total numbers of subject or in sex based subgroups

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Decreased MMP-9 (show MMP9 Proteins) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (show EGF Proteins) on MMP-9 (show MMP9 Proteins) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (show TNF Proteins), and hepatocyte growth factor (show HGF Proteins) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (show TIMP2 Proteins) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (show TIMP2 Proteins) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (show TIMP2 Proteins) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Results provide evidence for the utility of MMP9 (show MMP9 Proteins) and TIMP1 as markers of age- and lactocrine-sensitive porcine female reproductive tract development.

  2. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (show MMP9 Proteins), TIMP1, and NGAL (show LCN2 Proteins) (also MMP2 (show MMP2 Proteins) in 220 kDa complex) without proteolytic activity.

  3. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (show VEGFA Proteins), pro-MMP-9 (show MMP9 Proteins), MMP-2 (show MMP2 Proteins), VEGFR-1 (show FLT1 Proteins), VEGFR-2 (show KDR Proteins), and TIMP-1, which may contribute to the development of venous stenosis.

  4. Results indicate that leukemia inhibitory factor (LIF (show LIF Proteins)) and Oncostatin M (show OSM Proteins) increase the expression of MMP-1 (show MMP1 Proteins), MMP-3 (show MMP3 Proteins), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (show LIF Proteins) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (show MMP2 Proteins), MMP-9 (show MMP9 Proteins) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. TIMP-1 is upregulated in liver fibrosis and hepatocellular carcinoma, potentially implying diagnostic relevance in the non-invasive assessment of liver fibrosis or in HCC (show FAM126A Proteins) detection6. However, our study in TIMP-1-deficient mice did not confirm a functional role of TIMP-1 in the development of liver fibrosis or hepatocellular carcinoma.

  2. In obese mice, periodontitis caused the downregulation of MMP2 (show MMP2 Proteins), and upregulation of TIMP1 and TGF-beta1 (show TGFB1 Proteins) at transcriptional and translational levels

  3. gingival fibroblasts cell-based therapy is a promising approach to inhibit aneurysm progression and rupture through local production of Timp-1

  4. These results show that MMP-9 (show MMP9 Proteins)/TIMP-1 system disturbance and changes of histological structure in uteri tissue are involved in fluoride-induced reproductive dysfunctions.

  5. Tissue inhibitor of matrix metalloproteinases 1 (TIMP1) inhibition resensitized tumors to gemcitabine and radiotherapy.

  6. proteomic analysis of the mesenchymal stem cells secretome identified the TIMP-1 as a potential effector molecule responsible for the anti-angiogenic properties of MSC (show MSC Proteins)

  7. TIMP1 signaling via CD63 (show CD63 Proteins) leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  8. This study highlights a previously undescribed integral role for TIMP1 in both vascular network maturation and adaptations to ischemia or alterations in flow.

  9. TIMP-1 was identified as a selectively upregulated component secreted from immature astrocytes from human pluripotent stem cells.

  10. demonstrate that TIMP-2 (show TIMP2 Proteins) plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis

TIMP1 Protein Profile

Protein Summary

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Gene names and symbols associated with TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1)
  • TIMP metallopeptidase inhibitor 1 (Timp1)
  • tissue inhibitor of metalloproteinase 1 (Timp1)
  • Clgi protein
  • DKFZp468A0912 protein
  • EPA protein
  • EPO protein
  • HCI protein
  • Timp protein
  • TIMP-1 protein
  • TIMP1 protein

Protein level used designations for TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

GENE ID SPECIES
574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
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