TIMP1 Protein (AA 28-205) (His tag)
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- Target See all TIMP1 Proteins
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-205
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TIMP1 protein is labelled with His tag.
- Sequence
- Pro28-Arg205
- Characteristics
- A DNA sequence encoding the Mouse TIMP1 (P12032-1) (Pro28-Arg205) was expressed with a polyhistidine tag at the N-terminus.
- Purity
- >80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TIMP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Alternative Name
- TIMP1 (TIMP1 Products)
- Synonyms
- TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
- Background
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Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.
Synonym: Metalloproteinase inhibitor 1,Collagenase inhibitor 16C8 fibroblast,Erythroid-potentiating activity,EPA,TPA-S1,TPA-induced protein,Tissue inhibitor of metalloproteinases 1,TIMP-1,Timp, Timp-1
- Molecular Weight
- 19.88 kDa
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