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TIMP1 Protein (AA 28-205) (His tag)

TIMP1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >80 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505362
  • Target See all TIMP1 Proteins
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 28-205
    Origin
    • 10
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 15
    • 9
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TIMP1 protein is labelled with His tag.
    Sequence
    Pro28-Arg205
    Characteristics
    A DNA sequence encoding the Mouse TIMP1 (P12032-1) (Pro28-Arg205) was expressed with a polyhistidine tag at the N-terminus.
    Purity
    >80 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product TIMP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    Alternative Name
    TIMP1 (TIMP1 Products)
    Synonyms
    TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
    Background

    Background: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.

    Synonym: Metalloproteinase inhibitor 1,Collagenase inhibitor 16C8 fibroblast,Erythroid-potentiating activity,EPA,TPA-S1,TPA-induced protein,Tissue inhibitor of metalloproteinases 1,TIMP-1,Timp, Timp-1

    Molecular Weight
    19.88 kDa
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