Tumor Necrosis Factor Receptor Superfamily, Member 17 Proteins (TNFRSF17)

The protein encoded by TNFRSF17 is a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF17 Antibodies (128) and TNFRSF17 Kits (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF17 287034  
TNFRSF17 608 Q02223
TNFRSF17 21935 O88472
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Top TNFRSF17 Proteins at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HEK-293 Cells Human Fc Tag   50 μg Log in to see 5 to 8 Days
$402.56
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$5,262.31
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
HEK-293 Cells Human Fc Tag Human BCMA, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. Immobilized Human BCMA, Fc Tag  with a linear range of 0.31-1.25 μg/mL. 100 μg Log in to see 2 to 3 Days
$338.80
Details
Human Cells Mouse Fc Tag,His tag 100 μg Log in to see 14 to 16 Days
$382.80
Details
Human Cells Human Fc Tag,His tag 100 μg Log in to see 14 to 16 Days
$382.80
Details
Human Cells Rhesus Monkey Fc Tag 100 μg Log in to see 14 to 16 Days
$382.80
Details
Human Cells Rat Fc Tag 100 μg Log in to see 14 to 16 Days
$382.80
Details
Human Cells Mouse Fc Tag 100 μg Log in to see 14 to 16 Days
$382.80
Details

TNFRSF17 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , , , , ,
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Mouse (Murine) , , ,
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Top referenced TNFRSF17 Proteins

  1. Human TNFRSF17 Protein expressed in HEK-293 Cells - ABIN1344234 : Rennert, Schneider, Cachero, Thompson, Trabach, Hertig, Holler, Qian, Mullen, Strauch, Browning, Ambrose, Tschopp: A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth. in The Journal of experimental medicine 2000 (PubMed)
    Show all 4 Pubmed References

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) interaction partners

  1. Expression patterns of BAFF and its receptor BCMA differ according to lupus nephritis class.

  2. High BCMA expression is associated with primary central nervous system lymphoma.

  3. soluble BCMA sequesters circulating BAFF, thereby preventing it from performing its signaling to stimulate normal B-cell and plasma cell development, resulting in reduced polyclonal antibody levels in multiple myeloma patients.

  4. Studied expression of B-cell maturation antigen (BCMA) in osteoblasts and the toxic effect of chromium on its expression; found BCMA is involved in osteogenesis of osteoblasts; chromium downregulates expression of BCMA in osteoblasts.

  5. BCMA has other contributors for ligands binding except DxL motif. The affinity of BCMA for APRIL higher than for BAFF may be caused by the segment outside of the conservative DxL motif. Moreover, the exposition of new binding modes of BCMA2 interacting with APRIL may establish the foundation of designing novel drugs in the future

  6. New molecular mechanisms of in vivo Multiple Myeloma (MM) growth and immunosuppression critically dependent on BCMA and APRIL in the Bone marrow microenvironment, further supporting targeting this prominent pathway in MM.

  7. We have identified a specific serum protein, BCMA, as a novel independent marker for both monitoring and predicting outcomes for MM patients. We have shown that sBCMA is elevated in MM patients, and can be used to follow their disease status, PFS and OS.

  8. The expression levels of serum BAFF and the three receptors (TACI, BCMA and BAFF-R) in non-Hodgkin lymphoma patients were significantly higher than in healthy controls.

  9. Decreased BCMA expression on peripheral B cells according to severe disease activity suggests that BCMA plays an important regulating role in B-cell hyperactivity and immune tolerance homeostasis in systemic lupus erythematosus patients

  10. results suggest that Akt and JNK pathways are involved in the regulation of B-cell maturation antigen (BCMA)

  11. shedding of BCMA by gamma-secretase controls plasma cells in the bone marrow and yields a potential biomarker for B-cell involvement in human autoimmune diseases

  12. elevated serum levels in patients with Behcet's disease

  13. Data show significant differences in expression of tumour necrosis factor family (BAFF) receptors BAFF-R, BCMA and TACI in patients with and without anti-Jo-1 or anti-Ro52/anti-Ro60 autoantibodies.

  14. High BCMA expression is associated with breast cancer.

  15. BAFF and APRIL as well as their cognate receptors (BCMA, TACI) correlate with glioma grade. (Meta-analysis)

  16. The B cell maturation antigen (BCMA) is a tumor necrosis family receptor member that is predominantly expressed on terminally differentiated B cells and, upon binding to its ligands B cell activator of the TNF family and a proliferation inducing ligand.

  17. Activation of B cells through BCMA regulates spinal cord injury-induced autoimmunity via a proliferation-inducing ligand (APRIL) and B-cell-activating factor (BAFF).

  18. Data indicate that MAGE3, Survivin and B-cell maturation antigen (BCMA) mRNA-pulsed dendritic cells (DCs) are capable of stimulating tumor-associated antigens (TAA)-specific T-cell responses in multiple myeloma (MM) patients.

  19. Data indicate that B-cell maturation antigen (BCMA) is a suitable target for chimeric antigen receptor (CAR)-expressing T cells, and adoptive transfer of anti-BCMA-CAR-expressing T cells is a promising new strategy for treating multiple myeloma.

  20. B-cell maturation antigen (BCMA), an essential membrane protein for maintaining the survival of plasma cells, was identified as a glycoprotein exhibiting complex-type N-glycans at a single N-glycosylation site, asparagine 42.

TNFRSF17 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Gene names and symbols associated with TNFRSF17

  • TNF receptor superfamily member 17 (Tnfrsf17)
  • TNF receptor superfamily member 17 (TNFRSF17)
  • tumor necrosis factor receptor superfamily, member 17 (Tnfrsf17)
  • BCM protein
  • BCMA protein
  • CD269 protein
  • Tnfrsf13 protein
  • Tnfrsf13a protein
  • TNFRSF17 protein

Protein level used designations for TNFRSF17

tumor necrosis factor receptor superfamily member 17 , tumor necrosis factor receptor superfamily, member 17 , B cell maturation antigen , B-cell maturation factor , B-cell maturation protein

GENE ID SPECIES
287034 Rattus norvegicus
467905 Pan troglodytes
712212 Macaca mulatta
608 Homo sapiens
21935 Mus musculus
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