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ACOX1 Products

(Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

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The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured ACOX1 Categories

ACOX1 Antibodies

High quality antibodies with extensive validation data.

ACOX1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ACOX1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN6136442
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN3029856
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (3)
Cat. No. ABIN7445108
Quantity 100 μL
Datasheet Datasheet

Recommended ACOX1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953440
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951524
Quantity 96 tests
Datasheet Datasheet

Recommended ACOX1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121681
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305669
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419661
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ACOX1 products

Yan, Li, Peng, Long, Fan, Wang, Shi, Xie, Zhao, Yan: "The Fatty Acid β-Oxidation Pathway is Activated by Leucine Deprivation in HepG2 Cells: A Comparative Proteomics Study." in: Scientific reports, Vol. 7, Issue 1, pp. 1914, (2018) (PubMed).

Long, Muhamad, Yan, Yu, Fan, Wang, Li, Purnomoadi, Achmadi, Yan: "Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid β-oxidation pathway in HepG2 cells." in: Amino acids, Vol. 48, Issue 5, pp. 1297-307, (2017) (PubMed).

Grabelnych, Borovik, Tauson, Pobezhimova, Katyshev, Pavlovskaya, Koroleva, Lyubushkina, Bashmakov, Popov, Borovskii, Voinikov: "Mitochondrial energy-dissipating systems (alternative oxidase, uncoupling proteins, and external NADH dehydrogenase) are involved in development of frost-resistance of winter wheat seedlings." in: Biochemistry. Biokhimii?a, Vol. 79, Issue 6, pp. 506-19, (2014) (PubMed).

Kakizaki, Ito: "Engineering plant alternative oxidase function in mammalian cells: substitution of the motif-like sequence ENV for QDT diminishes catalytic activity of Arum concinnatum AOX1a expressed in HeLa cells." in: Applied biochemistry and biotechnology, Vol. 170, Issue 5, pp. 1229-40, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Pelletier, Rigden, Poon: "Diesel and biodiesels induce hepatic palmitoyl-CoA oxidase enzymatic activity through different molecular mechanisms in rats." in: Journal of biochemical and molecular toxicology, Vol. 26, Issue 6, pp. 235-40, (2012) (PubMed).

Costa-de-Oliveira, Sampaio-Marques, Barbosa, Ricardo, Pina-Vaz, Ludovico, Rodrigues: "An alternative respiratory pathway on Candida krusei: implications on susceptibility profile and oxidative stress." in: FEMS yeast research, Vol. 12, Issue 4, pp. 423-9, (2012) (PubMed).

Ghazalpour, Bennett, Petyuk, Orozco, Hagopian, Mungrue, Farber, Sinsheimer, Kang, Furlotte, Park, Wen, Brewer, Weitz, Camp, Pan, Yordanova, Neuhaus, Tilford, Siemers, Gargalovic, Eskin, Kirchgessner et al.: "Comparative analysis of proteome and transcriptome variation in mouse. ..." in: PLoS genetics, Vol. 7, Issue 6, pp. e1001393, (2011) (PubMed).

Bagattin, Hugendubler, Mueller: "Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 47, pp. 20376-81, (2010) (PubMed).

Gyamfi, Wan: "Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis." in: The Journal of biological chemistry, Vol. 284, Issue 14, pp. 9321-30, (2009) (PubMed).

Synonyms and alternative names related to ACOX1

acyl-CoA oxidase 1 (ACOX1), acyl-CoA oxidase 1, palmitoyl (acox1), acyl-CoA oxidase 1, palmitoyl L homeolog (acox1.L), acyl-CoA oxidase 1 (acox1), acyl-CoA oxidase 1 (Acox1), acyl-Coenzyme A oxidase 1, palmitoyl (Acox1), aco, acox, ACOX, Acox, AOX, D130055E20Rik, PALMCOX, Paox, PCOX1, RATACOA1, SCOX, wu:fb59h12, zgc:92584, zgc:114033

Protein level used designations for ACOX1

  • acyl-Coenzyme A oxidase 1, palmitoyl
  • peroxisomal acyl-coenzyme A oxidase 1
  • AOX
  • palmitoyl-CoA oxidase
  • Acyl-coenzyme A oxidase 1, peroxisomal
  • acyl-CoA oxidase 1, palmitoyl
  • peroxisomal acyl-coenzyme A oxidase 1-like
  • acyl-CoA oxidase, straight-chain
  • peroxisomal fatty acyl-CoA oxidase
  • straight-chain acyl-CoA oxidase
  • palmitoyl acyl-CoA oxidase 1
  • peroxisomal fatty acyl-coenzyme A oxidase
  • peroxisomal straight-chain Acyl-CoA oxidase
  • palmitoyl-CoA oxidase 1
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