This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008].
ADAM17
Origin: Human
Host: Mammalian Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM17
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM17
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Wang, Huang, Nayak, Matthews, Warburton, Shi, Sanchez-Esteban: "Strain-induced differentiation of fetal type II epithelial cells is mediated via the integrin ?6?1-ADAM17/tumor necrosis factor-?-converting enzyme (TACE) signaling pathway." in: The Journal of biological chemistry, Vol. 288, Issue 35, pp. 25646-57, (2013) (PubMed).
Aliases for ADAM17 Proteins
ADAM metallopeptidase domain 17 (ADAM17) Proteins a disintegrin and metallopeptidase domain 17 (Adam17) Proteins ADAM metallopeptidase domain 17b (adam17b) Proteins ADAM metallopeptidase domain 17 L homeolog (adam17.L) Proteins ADAM metallopeptidase domain 17 (Adam17) Proteins ADAM metallopeptidase domain 17a (adam17a) Proteins adam17 Proteins ADAM18 Proteins adam18 Proteins CD156B Proteins CD156b Proteins cd156b Proteins CSVP Proteins csvp Proteins fc20b01 Proteins NISBD Proteins si:dkey-81b15.2 Proteins TACE Proteins Tace Proteins tace Proteins wu:fc20b01 Proteins zgc:63886 Proteins