AKR1B1 Products
(Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
Categories
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009].
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Featured AKR1B1 Categories
AKR1B1 Antibodies
High quality antibodies with extensive validation data.
AKR1B1 ELISA Kits
Reliable ELISA kits for a wide range of species.
AKR1B1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AKR1B1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (6)
Cat. No.
ABIN3022391
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (5)
Cat. No.
ABIN389206
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, StM
Validations
- (5)
Cat. No.
ABIN6939403
Quantity
100 μg
Datasheet
Datasheet
Recommended AKR1B1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962618
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964712
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964711
Quantity
96 tests
Datasheet
Datasheet
Recommended AKR1B1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1344744
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121781
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN666726
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our AKR1B1 products
: "Investigation of synergistic mechanism and identification of interaction site of aldose reductase with the combination of gigantol and syringic acid for prevention of diabetic cataract." in: BMC complementary and alternative medicine, Vol. 16, Issue 1, pp. 286, (2017) (PubMed).: "Quantitative Analysis of Differential Proteome Expression in Epithelial-to-Mesenchymal Transition of Bladder Epithelial Cells Using SILAC Method." in: Molecules (Basel, Switzerland), Vol. 21, Issue 1, pp. 84, (2016) (PubMed).
: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).
: "Induction of PGF2? synthesis by cortisol through GR dependent induction of CBR1 in human amnion fibroblasts." in: Endocrinology, Vol. 155, Issue 8, pp. 3017-24, (2014) (PubMed).
: "Proteomic analysis of rat proximal tubule cells following stretch-induced apoptosis in an in vitro model of kidney obstruction." in: Journal of proteomics, Vol. 100, pp. 125-35, (2014) (PubMed).
: "Identification of multiple and distinct defects in prostaglandin biosynthetic pathways in eutopic and ectopic endometrium of women with endometriosis." in: Fertility and sterility, Vol. 100, Issue 6, pp. 1650-9.e1-2, (2013) (PubMed).
: "Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletal muscle." in: Experimental biology and medicine (Maywood, N.J.), Vol. 237, Issue 9, pp. 1068-83, (2012) (PubMed).
: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).
: "Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features." in: Journal of molecular biology, Vol. 379, Issue 5, pp. 991-1016, (2008) (PubMed).
: "Upregulation of aldose reductase during foam cell formation as possible link among diabetes, hyperlipidemia, and atherosclerosis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 6, pp. 1137-43, (2008) (PubMed).
Synonyms and alternative names related to AKR1B1
aldo-keto reductase family 1 member B (AKR1B1), aldo-keto reductase family 1 member B (Akr1b1), aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog (akr1b1.S), aldo-keto reductase family 1, member B1 (aldose reductase) (akr1b1), ADR, Akr1b3, Akr1b4, akr1b7, ALDR1, Aldr1, ALDRED, Alr, ALR-P-I, ALR2, AR, RATALDRED, zgc:86611Protein level used designations for AKR1B1
- Lii5-2 CTCL tumor antigen
- aldehyde reductase 1
- aldo-keto reductase family 1 member B1
- aldose reductase
- low Km aldose reductase
- AR
- Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene)
- aldo-keto reductase family 1, member B4 (aldose reductase)
- 20-alpha-HSD
- 20-alpha-hydroxysteroid dehydrogenase
- aldehyde reductase
- aldo-keto reductase family 1, member B1 (aldose reductase)
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