(Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))
The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010].
custom-made
AKR1D1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
AKR1D1
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
AKR1D1
Origin: Mouse
Host: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Catalog No. ABIN3126966
starts at
$20,480.57
Plus shipping costs $50.00, if applicable $20.00 dry ice
custom-made
AKR1D1
Origin: Human
Host: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Catalog No. ABIN3088846
starts at
$20,480.57
Plus shipping costs $50.00, if applicable $20.00 dry ice
Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).
Aliases for AKR1D1 Proteins
3-oxo-5-beta-steroid 4-dehydrogenase-like (LOC491379) Proteins aldo-keto reductase family 1 member D1 (AKR1D1) Proteins aldo-keto reductase family 1, member D1 (Akr1d1) Proteins aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (AKR1D1) Proteins 3o5bred Proteins CBAS2 Proteins SRD5B1 Proteins