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Full name:: Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit Proteins (PRKAG1)

On www.antibodies-online.com are 8 Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) Proteins from 6 different suppliers available. Additionally we are shipping PRKAG1 Antibodies (112) and many more products for this protein. A total of 124 PRKAG1 products are currently listed.

Synonyms:: AA571379, AMPKG, BB036179, MGC68503, Prkaac, Prkga1, wu:fa94d09, wu:fd12h04, zgc:63896

list all proteins	Gene Name	GeneID	UniProt
	PRKAG1	5571	P54619
Rat PRKAG1	PRKAG1	25520	P80385
	PRKAG1	19082	O54950
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Human Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) interaction partners

Data suggest different gamma-isoforms in AMPK (show PRKAA1 Proteins) can have different effects on enzyme activation; here, activation of AMPK (show PRKAA1 Proteins) by compound 991 is greater if AMPK (show PRKAA1 Proteins) contains PRKAG2 (show PRKAG2 Proteins) versus PRKAG1 or PRKAG3 (show PRKAG3 Proteins).
A subunit composition of AMPK (alpha2beta2gamma1) is preferred for colorectal cancer cell survival, at least in part, by stabilizing the tumor-specific expression of PGC1B.
Pin1 (show PIN1 Proteins) plays an important role in the pathogenic mechanisms underlying impaired glucose and lipid metabolism, functioning as a negative regulator of AMPK (show PRKAA1 Proteins)
Letter: report PRKAG1 frameshift mutations in colorectal cancer.
Electrogenic phosphate transport in sodium/phosphate cotransporter NaPi-IIa-expressing Xenopus oocytes is markedly decreased by the coexpression of constitutively active AMPKgammaR70Q, but not of AMPK (show PRKAA1 Proteins)(alphaK45R).
PRKAG1 interacts with DSCAM (show DSCAM Proteins) through its gamma subunit, and netrin-1 (show NTN1 Proteins) activates AMPK (show PRKAA1 Proteins) phosphorylation in cortical neurons.
Data indicate that except AMPK (show PRKAA1 Proteins)-alpha1, expressions of the other five AMPK (show PRKAA1 Proteins) subunits -alpha2, -beta1, -beta2, -gamma1 and -gamma2 are significantly higher in ovarian carcinomas.
Studies suggest insights into the regulation of AMPK (show PRKAA1 Proteins), its diverse biological actions, and therapeutic potential in the heart.
In breast cancer cells SESN2 (show SESN2 Proteins) is associated with AMPK (show PRKAA1 Proteins).
Conclude that cTnI (show TNNI3 Proteins) phosphorylation by AMPK (show PRKAA1 Proteins) may represent a novel mechanism of regulation of cardiac function.

Mouse (Murine) Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) interaction partners

These results emphasize the clinical relevance of activating AMPK (show PRKAA1 Proteins) in the liver to combat non-alcoholic fatty liver disease.
Data indicate that a diet high in iron improves glucose tolerance by activating AMPK (show PRKAA1 Proteins) through mechanisms that include deacetylation.
In R70Qgamma1-expressing mice, there is an increase in muscle glycogen synthase activity associated with an increase in exercise capacity.
AMPK (show PRKAA1 Proteins) is not necessary for exercise training-induced increases in mitochondrial markers, but it is essential for fiber type IIb to IIa/x transformation and increases in hexokinase II protein[AMP-activated protein kinase (show PRKAA2 Proteins) gamma1]

Pig (Porcine) Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) interaction partners

Cow (Bovine) Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1) interaction partners

Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells
isolation and characterization of the gene for the noncatalytic bovine gamma1 subunit of AMPK (show PRKAA1 Proteins)

PRKAG1 Protein Profile

Protein Summary

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog (prkag1.S)
protein kinase, AMP-activated, gamma 1 non-catalytic subunit (prkag1)
protein kinase AMP-activated non-catalytic subunit gamma 1 (PRKAG1)
protein kinase AMP-activated non-catalytic subunit gamma 1 (Prkag1)
protein kinase, AMP-activated, gamma 1 non-catalytic subunit (Prkag1)

AA571379 protein
AMPKG protein
BB036179 protein
MGC68503 protein
Prkaac protein
Prkga1 protein
wu:fa94d09 protein
wu:fd12h04 protein
zgc:63896 protein

Protein level used designations for PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit , 5'-AMP-activated protein kinase subunit gamma-1 , AMPK-activated protein kinase gamma-1 subunit , AMP-activated protein kinase, noncatalytic gamma-1 subunit , 5'-AMP-activated protein kinase subunit gamma-1-like , 5'-AMP-activated protein kinase, gamma-1 subunit , AMPK gamma-1 chain , AMPK gamma1 , AMPK subunit gamma-1 , AMPKg , Protein kinase AMP-activated gamma , 38 kDa subunit , 5'-AMP-activated protein kinase gamma-1 subunit , AMP-activated protein kinase subunit gamma 1 (non-catalytic subunit)

GENE ID	SPECIES
398958	Xenopus laevis
406440	Danio rerio
451872	Pan troglodytes
486559	Canis lupus familiaris
709298	Macaca mulatta
100034096	Equus caballus
100158499	Xenopus (Silurana) tropicalis
100356542	Oryctolagus cuniculus
100390042	Callithrix jacchus
100442951	Pongo abelii
100607037	Nomascus leucogenys
5571	Homo sapiens
25520	Rattus norvegicus
19082	Mus musculus
414426	Sus scrofa
282324	Bos taurus

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