IL15RA antibody

Catalog No. ABIN1077442

Product Details anti-IL15RA Antibody

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL15RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Multiple isoforms of IL-15RA are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal IL-15RA antibody was raised against a 16 amino acid peptide near the center of human IL-15RA.

Isotype: IgG

Application Details

Application Notes: IL-15RA antibody can be used for detection of IL-15RA by Western blot at 1 - 2 μg/mL.

Comment:

(IN) Interleukin-15 receptor subunit alpha

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: IL15RA (IL15RA Products)

Background: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
Synonyms: Interleukin-15 receptor subunit alpha, IL15RA, CD215

Molecular Weight: 39 kDa

Gene ID: 3601

NCBI Accession: NP_001243694

Pathways: JAK-STAT Signaling