IL15RA antibody

Catalog No. ABIN1077442

This Rabbit Monoclonal antibody specifically detects IL15RA in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for IL15RA antibody (ABIN1077442)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL15RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL15RA Antibody

Specificity: Multiple isoforms of IL-15RA are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal IL-15RA antibody was raised against a 16 amino acid peptide near the center of human IL-15RA.

Isotype: IgG

Application Details

Application Notes: IL-15RA antibody can be used for detection of IL-15RA by Western blot at 1 - 2 μg/mL.

Comment:

(IN) Interleukin-15 receptor subunit alpha

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: IL15RA

Background: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
Synonyms: Interleukin-15 receptor subunit alpha, IL15RA, CD215

Molecular Weight: 39 kDa

Gene ID: 3601

NCBI Accession: NP_001243694

Pathways: JAK-STAT Signaling