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Transportin 1 antibody

TNPO1 Reactivity: Human, Mouse, Monkey, Rabbit WB, ELISA, IP, FACS, ICC, IHC (p), IF Host: Mouse Monoclonal D45 unconjugated
Catalog No. ABIN108619
  • Target See all Transportin 1 (TNPO1) Antibodies
    Transportin 1 (TNPO1)
    Reactivity
    Human, Mouse, Monkey, Rabbit
    Host
    • 38
    • 3
    • 1
    Mouse
    Clonality
    • 39
    • 3
    Monoclonal
    Conjugate
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Transportin 1 antibody is un-conjugated
    Application
    • 40
    • 18
    • 17
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    Protein A
    Immunogen
    Recombinant his tagged transportin1 (Human)
    Clone
    D45
    Isotype
    IgG1
    Top Product
    Discover our top product TNPO1 Primary Antibody
  • Application Notes
    Optimal antibody dilution should be determined by titration, however as a guideline try,Flow Cyt: Use 1 μg for 106 cells.ICC/IF: Use a concentration of 5 μg/mL.IHC-P: Use a concentration of 1 μg/mL. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.WB: 1:800. Detects a band of approximately 93 kDa (predicted molecular weight: 107 kDa)
    Comment

    Myeloma, fusion partners: SP2/0

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Yu, Boyce, Wands, Bond, Bertozzi, Kohler: "Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 13, pp. 4834-9, (2012) (PubMed).

    Brelstaff, Lashley, Holton, Lees, Rossor, Bandopadhyay, Revesz: "Transportin1: a marker of FTLD-FUS." in: Acta neuropathologica, Vol. 122, Issue 5, pp. 591-600, (2011) (PubMed).

    Gu, Tsuji, Jarboui, Yeo, Sheehy, Hall, Gautier: "Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import." in: Retrovirology, Vol. 8, pp. 17, (2011) (PubMed).

    Chen, Shao, Cobos, Wang, Gao: "4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone [corrected] induces CRM1-dependent p53 nuclear accumulation in human bronchial epithelial cells." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 116, Issue 1, pp. 206-15, (2010) (PubMed).

    Janiszewska, De Vito, Le Bitoux, Fusco, Stamenkovic: "Transportin regulates nuclear import of CD44." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30548-57, (2010) (PubMed).

    Favre, Camps, Arod, Chabert, Rommel, Pasquali: "Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation." in: Proteomics, Vol. 8, Issue 21, pp. 4560-76, (2008) (PubMed).

  • Target
    Transportin 1 (TNPO1)
    Alternative Name
    Transportin 1  (TNPO1 Products)
    Synonyms
    IPO2 antibody, KPNB2 antibody, MIP antibody, MIP1 antibody, TRN antibody, TNPO1 antibody, AU021749 antibody, D13Ertd688e antibody, Kpnb2 antibody, ATTRN1 antibody, F12A24.13 antibody, F12A24_13 antibody, TRANSPORTIN 1 antibody, transportin 1 antibody, DKFZp469O204 antibody, transportin 1 antibody, transportin-1 antibody, transportin 1 S homeolog antibody, TNPO1 antibody, LOC738932 antibody, tnpo1 antibody, Tnpo1 antibody, tnpo1.S antibody, TRN1 antibody
    Background
    Synonyms:
    Importin beta 2 antibody,IPO 2 antibody,IPO2 antibody,Karyopherin (importin) beta 2antibody,Karyopherin beta 2 antibody,KPN B2 antibody,KPNB 2 antibody,KPNB2 antibody,M9 interacting proteinantibody,M9 region interacting protein antibody,M9 region interaction protein antibody,M9-interacting proteinantibody,MIP 1 antibody,MIP antibody,MIP1 antibody,TNPO 1 antibody,TNPO1 antibody,Transportinantibody,Transportin-1 antibody,Transportin1 antibody,TRN antibody
    OMIM
    602901
    Pathways
    PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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