Annexin a1 antibody

Catalog No. ABIN6939603

Product Details anti-Annexin a1 Antibody

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogen: Recombinant full length human Annexin A1 protein

Clone: ANXA1-1671

Isotype: IgG2b kappa

Application Details

Application Notes:

Positive Control: A431 and K562 cell lysates, human esophagus, placenta and prostate tissues.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: ANXA1 (ANXA1 Products)

Synonyms: anx1a antibody, anxa1 antibody, wu:fa01d11 antibody, wu:fa05d11 antibody, wu:fk69h01 antibody, MGC64363 antibody, anx1 antibody, lpc1 antibody, MGC89164 antibody, ANXA1 antibody, ANX1 antibody, LPC1 antibody, p35 antibody, Anx-1 antibody, Anx-A1 antibody, C430014K04Rik antibody, Lpc-1 antibody, Lpc1 antibody, Anx1 antibody, annexin A1a antibody, annexin A1 antibody, annexin A1 L homeolog antibody, Annexin A1 antibody, anxa1a antibody, anxa1 antibody, anxa1.L antibody, ANXA1 antibody, LOC100335033 antibody, Anxa1 antibody

Background: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Molecular Weight: 35kDa

Gene ID: 301

UniProt: P04083

Pathways: Hormone Transport