Mesp2 antibody (AA 37-94)

Catalog No. ABIN1098148

This Mouse Monoclonal antibody specifically detects Mesp2 in ELISA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for Mesp2 antibody (AA 37-94) (ABIN1098148)

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Mesp2 antibody is un-conjugated

Application: ELISA

Clone: 1B3F9

Product Details anti-Mesp2 Antibody

Binding Specificity: AA 37-94

Purpose: MESP2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MESP2 (AA: 37-94 ) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Mesp2 antibody (ABIN1098148)

Qiu, Zhou, Jiang, Ji, Ding, Lv, Liu, Tang, Cheng, Qiu: "Mutation analysis of MESP2, HES7 and DUSP6 gene exons in patients with congenital scoliosis." in: Studies in health technology and informatics, Vol. 176, pp. 52-5, (2012) (PubMed).

Cornier, Staehling-Hampton, Delventhal, Saga, Caubet, Sasaki, Ellard, Young, Ramirez, Carlo, Torres, Emans, Turnpenny, Pourquié: "Mutations in the MESP2 gene cause spondylothoracic dysostosis/Jarcho-Levin syndrome." in: American journal of human genetics, Vol. 82, Issue 6, pp. 1334-41, (2008) (PubMed).

Target Details for Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Alternative Name: MESP2

Background: This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Molecular Weight: 41.8 kDa

Gene ID: 145873

UniProt: Q0VG99