APOA5 antibody

Catalog No. ABIN1105412

The Mouse Monoclonal anti-APOA5 antibody has been validated for WB and EIA. It is suitable to detect APOA5 in samples from Human.

Quick Overview for APOA5 antibody (ABIN1105412)

Target: APOA5 (Apolipoprotein A-V (APOA5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOA5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 1G5G9 (c)

Product Details anti-APOA5 Antibody

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.03 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for APOA5

Target: APOA5 (Apolipoprotein A-V (APOA5))

Alternative Name: Apolipoprotein A V (ApoA V)

Background: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70 % lowerconcentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.Synonyms: APOA5, Apo-AV, ApoA-V, Apolipoprotein A-V, RAP3, Regeneration-associated protein 3

Gene ID: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism