APOA5 antibody

Catalog No. ABIN708701

The Rabbit Polyclonal anti-APOA5 antibody is suitable to detect APOA5 in samples from Human. It has been validated for IF, IHC (p) and IHC (fro).

Quick Overview for APOA5 antibody (ABIN708701)

Target: APOA5 (Apolipoprotein A-V (APOA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOA5 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-APOA5 Antibody

Purpose: Apolipoprotein A V Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APOA5

Isotype: IgG

Application Details

Application Notes: IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for APOA5

Target: APOA5 (Apolipoprotein A-V (APOA5))

Alternative Name: Apolipoprotein A V

Background:

Synonyms: APOA5, Apolipoprotein A V, Apo-AV, ApoA-V, Apoa5, APOA5_HUMAN, ApoAV, Apolipoprotein A-V, Apolipoprotein A5, RAP3, Regeneration associated protein 3, Regeneration-associated protein 3.

Background: The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009].

Gene ID: 116519

UniProt: Q6Q788

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism