MMP2 antibody

Catalog No. ABIN110556

The Rabbit Polyclonal anti-MMP2 antibody (ABIN110556) specifically detects MMP2 in WB, IHC and IP. The antibody is reactive with Rat samples.

Quick Overview for MMP2 antibody (ABIN110556)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-MMP2 Antibody

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

Target Details for MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Alternative Name: MMP2 (Mammalian Matrix Metalloproteinase, 72kDa Type IV Collagenase, Gelatinase-A)

Background: The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes1. After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N- terminal propeptide domain is cleaved to generate the active forms of MMP2 . MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.

Pathways: Activation of Innate immune Response