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CD25 antibody

Name: CD25 antibody
SKU: ABIN1106134
Price: 516 USD
Availability: InStock

IL2RA Reactivity: Human FACS, Func Host: Mouse Monoclonal B-B10 unconjugated

FACS

1 image

Catalog No. ABIN1106134

Datasheet as PDF

Target See all CD25 (IL2RA) Antibodies

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
Reactivity
168

117

36

10

10

5

3

2

2

2

1

1
Human
Host
138

83

80

2

2

1

1
Mouse
Compatible Secondaries
Clonality
231

70

4
Monoclonal
Conjugate
121

33

28

24

21

11

6

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD25 antibody is un-conjugated
Application
225

86

56

53

44

40

23

18

15

13

8

8

6

6

4

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Cross-Reactivity (Details)

Species reactivity (tested):Human.

Purification

Ion Exchange Chromatography.

Sterility

0.22 μm filtered

Immunogen

PHA activated T cells. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Clone

B-B10

Isotype

IgG1

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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.

Preservative

Without preservative

Storage

4 °C

Storage Comment

Store the antibody undiluted at 2-8 °C.
Target

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name

CD25 / IL2RA (IL2RA Products)

Background

IL-2R (T-cell growth factor receptor) consists of a chain of 55 kDa (also known as Tac antigen or p55 or alpha chain) and a p75 or beta chain. IL-2RA is over-expressed on the surface of activated Tcells, HTLV-1 or -2 positive T-cell lines, and moderately expressed on activated B-cells, NK-cells, and macrophages. CD25 Molecule alone appears to function as a low affinity receptor and associates wtih CD122 (IL-2R beta chain, p75) and CD132 (common gamma chain) to form the high affinity IL-2 receptor complex.Synonyms: IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, Interleukin-2 receptor alpha chain, TAC antigen, p55

Gene ID

3559

NCBI Accession

NP_000408

UniProt

P01589

Pathways

JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation