CD4 antibody (FITC)

Catalog No. ABIN1106346

This anti-CD4 antibody is a Mouse Monoclonal antibody detecting CD4 in FACS. Suitable for Human.

Quick Overview for CD4 antibody (FITC) (ABIN1106346)

Target: CD4

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: Edu-2

Product Details anti-CD4 Antibody (FITC)

Specificity: Anti CD4 (Edu-2) recognizes the CD4 antigen (a 55 kDa glycoprotein). Testing by flow cytometry using a 'lyse-wash'method on whole blood from healthy donors showed the following values expressed in terms of % of the total lymphocyte count: Product code: AM39008FC-N (anti-CD4 FITC) Mean % positive: 45,36 S.D.:5,20 % CV: 11,46

Purification: Affinity chromatography

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 0.01 M sodium phosphate, 0.15 M NaCl, pH 7.3, 0.2 % BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. This product is photosensitive and should be protected from light.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4 plays a role in the recognition of foreign antigens presented to T cells by MHC class II molecules. Furthermore, this antigen acts as a receptor for HIV-1 by binding the viral protein gp120. The CD4 antigen is present on most thymocytes and a subpopulation of peripheral blood T cells, called T helper cells (Th). In addition, CD4 is expressed on monocytes and weak on macrophages.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gene ID: 920

NCBI Accession: NP_000607

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events