The Rabbit Polyclonal anti-ITGA4 antibody has been validated for WB, IP, IF and IHC (p). It is suitable to detect ITGA4 in samples from Human, Mouse and Rat.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Reconstitution
1.2 % sodium acetate or neutral PBS. If 0.5 mL of PBS is used, the antibody concentration will be 100 μg/mL.
Buffer
50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target
ITGA4
(Integrin alpha 4 (ITGA4))
Alternative Name
CD49d / ITGA4
Background
The integrin family includes cell surface receptors for extracellular matrix components as well as receptors involved in various aspects of leukocyte adhesion. Integrin alpha chain 4 (ITGA4) is assigned to 2q31-q32. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia.Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4