GFI1B antibody (N-Term)

Catalog No. ABIN1107348

The Rabbit Polyclonal anti-GFI1B antibody (ABIN1107348) specifically detects GFI1B in WB and IHC (p). The antibody is reactive with Human, Mouse, Rat, Cow and Dog samples.

Quick Overview for GFI1B antibody (N-Term) (ABIN1107348)

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFI1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GFI1B Antibody

Binding Specificity: N-Term

Sequence: MPRSFLVKSK MAHTYHQPRV QEDEPLWPPA LTPVPRDQAP SNSPVLSTLF

Cross-Reactivity (Details): Species reactivity (expected):Dog, Rat, Mouse, BovineSpecies reactivity (tested):Human

Purification: Purified on peptide immunoaffinity column

Immunogen: The immunogen for anti-GFI1B antibody: synthetic peptide directed towards the N terminal of human GFI1B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term

Expiry Date: 12 months

Target Details for GFI1B

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Alternative Name: GFI1B

Background: GFI1B acts in the late stage of erythroid differentiation as a transcriptional repressor. GATA-1 and NF-Y both contribute to erythroid-specific transcriptional activation of the Gfi-1B promoter. This zinc finger protein mediates erythroid expansion and has a role in normal erythropoiesis.Synonyms: Growth factor independent protein 1B, Potential regulator of CDKN1A translocated in CML, Zinc finger protein Gfi-1b

Gene ID: 8328

NCBI Accession: NP_004179

Pathways: Cellular Response to Molecule of Bacterial Origin