IL12A antibody

Catalog No. ABIN1107787

This Mouse Monoclonal antibody specifically detects IL12A in FACS and Func. It exhibits reactivity toward Human.

Quick Overview for IL12A antibody (ABIN1107787)

Target: IL12A (Interleukin 12 alpha (IL12A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL12A antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: B-T21

Product Details anti-IL12A Antibody

Specificity: This antibody recognizes both natural and recombinant Human IL-12 p35 + p70

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography.

Sterility: 0.22 μm filtered

Immunogen: Recombinant Human IL-12.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for IL12A

Target: IL12A (Interleukin 12 alpha (IL12A))

Alternative Name: Interleukin-12 alpha / IL12A

Background: Interleukin 12 (IL12) is an important cytokine produced by a variety of immune effector cells that leads to a type 1 helper T cell (Th1) response. IL12 also directs T cells to the skin via induction of cutaneous lymphocyte antigen (CLA) expression. Interleukin 12 is a heterodimeric cytokine (p70), composed of two covalently linked subunits, p35 and p40 and is secreted primarily by activated B cells.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1

Gene ID: 3592

NCBI Accession: NP_000873

UniProt: P29459

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation