Lipase A antibody

Catalog No. ABIN1108046

The Mouse Monoclonal anti-Lipase A antibody has been validated for WB and EIA. It is suitable to detect Lipase A in samples from Human.

Quick Overview for Lipase A antibody (ABIN1108046)

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lipase A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 9G7F12

Product Details anti-Lipase A Antibody

Specificity: This antibody reacts to LAL.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0,03 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Alternative Name: LIPA

Background: Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.Synonyms: Acid cholesteryl ester hydrolase, Cholesteryl esterase, EC=3.1.1.13, LAL, LIPA, Lipase A, Lysosomal acid lipase/cholesteryl ester hydrolase, Sterol esterase

Gene ID: 3988