NK2 Homeobox 5 antibody
Quick Overview for NK2 Homeobox 5 antibody (ABIN1108466)
Target
See all NK2 Homeobox 5 (NKX2-5) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody reacts to NKX2.5
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein G
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, 0,03 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- NK2 Homeobox 5 (NKX2-5)
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Alternative Name
- NKX2-5
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Background
- NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.Synonyms: CSX, Cardiac-specific homeobox, Homeobox protein CSX, Homeobox protein NK-2 homolog E, Homeobox protein Nkx-2.5, NKX2.5, NKX2E
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Molecular Weight
- 35 kDa
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Gene ID
- 1482
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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