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PCNA antibody

PCNA Reactivity: Human, Mouse, Rat WB, IF, IHC (p), IHC (fro) Host: Mouse Monoclonal IML-83 unconjugated
Catalog No. ABIN1108598
  • Target See all PCNA Antibodies
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Reactivity
    • 200
    • 141
    • 140
    • 51
    • 26
    • 25
    • 20
    • 18
    • 17
    • 17
    • 16
    • 12
    • 10
    • 10
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 127
    • 86
    • 3
    Mouse
    Clonality
    • 127
    • 88
    • 1
    Monoclonal
    Conjugate
    • 104
    • 16
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCNA antibody is un-conjugated
    Application
    • 177
    • 64
    • 60
    • 59
    • 49
    • 47
    • 44
    • 36
    • 29
    • 17
    • 14
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody reacts to PCNA.
    Purification
    Affinity chromatography
    Immunogen
    Protein A fusion protein
    Clone
    IML-83
    Isotype
    IgG2a
    Top Product
    Discover our top product PCNA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1.2 % sodium acetate or neutral PBS
    Concentration
    0,1 mg/mL
    Buffer
    1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Alternative Name
    PCNA (PCNA Products)
    Background
    Proliferating cell nuclear antigen (PCNA) was originally identified by immunofluorescence as a nuclear protein whose appearance correlated with the proliferative state of the cell. PCNA /cyclin has been localized by in situ hybridization to the short arm of human chromosome 20 with a peak of grains over band 20p13. PCNA gene is present in single copy and has 6 exons. It spans 4,961 bp. Synthesis of the nuclear protein cyclin and DNA in quiescent mouse fibroblasts is coordinately induced by serum and purified growth factors. PCNA controls establishment of sister chromatid cohesion during S phase.Synonyms: Cyclin, Proliferating Cell Nuclear Antigen
    Gene ID
    5111
    NCBI Accession
    NP_002583
    UniProt
    P12004
    Pathways
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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