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RPS6KB1 antibody

RPS6KB1 Reactivity: Human WB, IHC (p), FACS, EIA Host: Mouse Monoclonal 5G9 unconjugated
Catalog No. ABIN1108904
  • Target See all RPS6KB1 Antibodies
    RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
    Reactivity
    • 320
    • 229
    • 227
    • 55
    • 23
    • 21
    • 20
    • 17
    • 12
    • 9
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 304
    • 32
    • 2
    • 2
    Mouse
    Clonality
    • 308
    • 33
    Monoclonal
    Conjugate
    • 162
    • 19
    • 16
    • 14
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    This RPS6KB1 antibody is un-conjugated
    Application
    • 276
    • 131
    • 104
    • 94
    • 91
    • 72
    • 59
    • 30
    • 24
    • 18
    • 17
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificity
    Recognizes RPS6KB1 / STK14A
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Purified
    Clone
    5G9
    Isotype
    IgG1
    Top Product
    Discover our top product RPS6KB1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.05 % Sodium Azide, 0.5 % protein stabilizer
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
    Alternative Name
    RPS6KB1 / STK14A (RPS6KB1 Products)
    Background
    This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.Synonyms: 70 kDa ribosomal protein S6 kinase 1, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, Serine/threonine-protein kinase 14A, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K 1
    Molecular Weight
    59 kDa
    Gene ID
    6198
    Pathways
    PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect
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