SOX12 antibody (C-Term)

Catalog No. ABIN1109105

The Rabbit Polyclonal anti-SOX12 antibody is suitable to detect SOX12 in samples from Human, Mouse, Dog and Rat. It has been validated for WB.

Quick Overview for SOX12 antibody (C-Term) (ABIN1109105)

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Reactivity: Human, Mouse, Dog, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOX12 Antibody

Binding Specificity: C-Term

Sequence: DCSALDRDPD LQPPSGTSHF EFPDYCTPEV TEMIAGDWRP SSIADLVFTY

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: The immunogen for anti-SOX12 antibody: synthetic peptide directed towards the C terminal of human SOX12.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: SOX12

Background: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The SOX12 gene encodes a protein that was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.Synonyms: SOX-22 protein, SOX22, SRY-box 12, SRY-box 22, Transcription factor SOX-12

Gene ID: 6666

NCBI Accession: NP_008874