SOX12 antibody (AA 31-110)

Catalog No. ABIN7863858

The Mouse Monoclonal anti-SOX12 antibody is suitable to detect SOX12 in samples from Human. It has been validated for FACS.

Quick Overview for SOX12 antibody (AA 31-110) (ABIN7863858)

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-SOX12-1E4

Product Details anti-SOX12 Antibody

Binding Specificity: AA 31-110

Purpose: SOX12 (Transcription Factor) Antibody

Specificity: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa31-110) of human SOX12 protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: SOX12

Background:

Homo sapiens SRY (sex determining region Y) box 12, Protein SOX-22, SOX 12 protein, SRY (sex determining region Y) box 12, SRY (sex determining region Y) box 22, SRY related HMG box gene 22, Transcription factor Sox-12

HeLa or U87 cells.

Molecular Weight: 34.12kDa

Gene ID: 6666, 43627

UniProt: O15370