TP53I3 antibody (N-Term)

Catalog No. ABIN1109287

The Mouse Monoclonal anti-TP53I3 antibody (Clone AT1C9) (ABIN1109287) specifically detects TP53I3 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for TP53I3 antibody (N-Term) (ABIN1109287)

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TP53I3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT1C9

Product Details anti-TP53I3 Antibody

Binding Specificity: AA 1-332, N-Term

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human TP53I3 (1-332aa) purified from E. coli

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TP53I3

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Alternative Name: TP53I3

Background: TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.Synonyms: PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein

Gene ID: 9540

UniProt: Q53FA7

Pathways: p53 Signaling