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Tumor Protein p73 antibody (C-Term)
TP73
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Tumor Protein p73 Antibody
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Target
See all Tumor Protein p73 (TP73) Antibodies
Tumor Protein p73 (TP73)
(Tumor Protein P73 (TP73))
Binding Specificity
All epitopes for Tumor Protein p73 antibodies
C-Term
Reactivity
All reactivities for Tumor Protein p73 antibodies
Human, Mouse, Rat
Host
All hosts for Tumor Protein p73 antibodies
Rabbit
Clonality
All clonalities for Tumor Protein p73 antibodies
Polyclonal
Conjugate
All conjugates for Tumor Protein p73 antibodies
This Tumor Protein p73 antibody is un-conjugated
Application
All applications for Tumor Protein p73 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects Tumor protein p73 (alpha) at C-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Immunogen affinity purified
Immunogen
A peptide mapping at the C-terminal end of human P73a .Remarks: Sequence differs from the related rat sequence by single amino acid.
Isotype
IgG
Top Product
Discover our top product TP73 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer
50 % glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for Tumor Protein p73
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Target
Tumor Protein p73 (TP73)
(Tumor Protein P73 (TP73))
Abstract
TP73 Products
Synonyms
P73 antibody, Trp73 antibody, TP73 antibody, tp73 antibody, Tp73 antibody, p73 antibody, TAp73 antibody, zp73theta antibody, tumor protein p73 antibody, transformation related protein 73 antibody, TP73 antibody, Tp73 antibody, tp73 antibody, Trp73 antibody
Background
P73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation. Moreover, p73 was phosphorylated in vivo in response to ionizing radiation. p73, a member of the p53 family of tumour-suppressor proteins, can also induce apoptosis.p73 gene is mapped to chromosome 1p36. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.Synonyms: p53-like transcription factor, p53-related protein
Gene ID
7161
NCBI Accession
NP_001119712
UniProt
O15350
Pathways
Regulation of Cell Size , Positive Regulation of Response to DNA Damage Stimulus
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