VNN2 antibody
Quick Overview for VNN2 antibody (ABIN1109468)
Target
See all VNN2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- This antibody reacts with human GPI-80. Does not react with mouse or rat Neutrophil.
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Purification
- Protein A agarose
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Immunogen
- PMA activated human neutrophil
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store (in aliquots) at -20 °C.
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- VNN2 (Vanin 2 (VNN2))
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Alternative Name
- Vanin-2 / FOAP-4
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Background
- The GPI-80 Molecule (80 kDa) recognized by this antibody (clone 3H9) was shown to be present on human neutrophils. When 3H9 was added with a neutrophil stimulant (fMLP), the inhibition of neutrophil adherence was observed after 60 minutes incubation. 3H9 enhanced not only fMLP-induced chemotaxis but random migration of neutrophil as well. Furthermore, 3H9 clearly discriminated neutrophils from both basophils and eosinophils derived from humans.Synonyms: Glycosylphosphatidyl inositol-anchored protein GPI-80, VNN2, Vascular non-inflammatory molecule 2
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Gene ID
- 8875
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NCBI Accession
- NP_001229279
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UniProt
- O95498
Target
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