VNN2 antibody (AA 320-400)

Catalog No. ABIN7232108

The Rabbit Polyclonal anti-VNN2 antibody is suitable to detect VNN2 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for VNN2 antibody (AA 320-400) (ABIN7232108)

Target: VNN2 (Vanin 2 (VNN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VNN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VNN2 Antibody

Binding Specificity: AA 320-400

Purpose: Rabbit Anti-VNN2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of VNN2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human VNN2 protein at AA range: 320-400

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VNN2

Target: VNN2 (Vanin 2 (VNN2))

Alternative Name: VNN2

Background: Vascular non-inflammatory molecule 2, Vanin-2, Glycosylphosphatidyl inositol-anchored protein GPI-80, Protein FOAP-4VNN2 product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. VNN2 lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for VNN2.

Molecular Weight: 57kD

Gene ID: 8875

UniProt: O95498