Tissue factor antibody

Catalog No. ABIN112492

This Mouse Monoclonal antibody specifically detects Tissue factor in WB, FACS, IF, IHC (fro) and EIA. It exhibits reactivity toward Human and Primate.

Quick Overview for Tissue factor antibody (ABIN112492)

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tissue factor antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: TF9-10H10

Product Details anti-Tissue factor Antibody

Specificity: This antibody is specific for an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.

Purification: Affinity Chromatography on Protein G.

Immunogen: Denatured Tissue factor isolated from human brain by the Factor VII affinity method.

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot. Flow Cytometry. Immunofluorescence. Immunohistology on Frozen and Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative and 200 mM Mannitol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Tissue factor

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Alternative Name: CD142 / Tissue Factor

Background: CD142, also known as Tissue factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation.Synonyms: Coagulation factor III, F3, TF, Thromboplastin

Gene ID: 2152

NCBI Accession: NP_001984

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling