TGFA antibody (Transforming Growth Factor, alpha)

Details for Product anti-TGFA Antibody No. ABIN114031, Supplier: Log in to see
Antigen
  • TFGA
  • LOC100009482
  • TGF alpha
  • TGFA
  • wa-1
  • wa1
  • RATTGFAA
  • TGFAA
  • NV15606
  • si:ch211-10e8.7
  • transforming growth factor alpha
  • transforming growth factor alpha L homeolog
  • transforming growth factor-alpha
  • transforming growth factor, alpha
  • TGFA
  • TGF-A
  • Tgfa
  • tgfa.L
  • LOC100121300
  • LOC100009150
  • tgfa
Alternatives
anti-Human TGFA antibody for Western Blotting
Reactivity
Cow (Bovine), Human, Rat (Rattus)
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Host
Sheep
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Clonality
Polyclonal
Conjugate
This TGFA antibody is un-conjugated
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Application
Enzyme Immunoassay (EIA)
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Options
Supplier
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Immunogen Mature human recombinant TGF-alpha conjugated to KLH.
Specificity This antibody detects Transforming Growth Factor alpha. Does not react with EGF or TGF-beta.
Purification Ion Exchange chromatography
Plasmids, Primers & others Plasmids, Primers & others TGFA products on genomics-online (e.g. as negative or positive controls)
Antigen Transforming Growth Factor, alpha (TGFA)
Alternative Name TGF-alpha (TGFA) (TGFA Antibody Abstract)
Background TGF-alpha is a 50 amino acid EGF-related polypeptide expressed in a range of tissues, including skin, pancreas, liver, duodenum, salivary glands, urinary and respiratory systems, and the developing and mature central nervous system (CNS). TGF-alpha is produced by monocytes, keratinocytes and neuronal cells and stimulates the proliferation of a range of epidermal and epithelial cells, through binding to the epidermal growth factor receptor (EGFR). TGFalpha is mitogenic for multipotent neural progenitors and is involved in astrogliosis.Synonyms: EGF-like TGF, ETGF, TGF type 1, Transforming growth factor alpha
Gene ID 7039
NCBI Accession NP_001093161
UniProt P01135
Pathways NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway
Application Notes ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 3.1 mg/mL
Buffer Borate buffered saline, pH 8.4, 0.09 % Sodium Azide (NaN3)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. Dilute only prior to immediate use
Storage 4 °C/-20 °C
Storage Comment Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Ju, Velu, Vass, Papageorge, Lowy: "Tumorigenic transformation of NIH 3T3 cells by the autocrine synthesis of transforming growth factor alpha." in: The New biologist, Vol. 3, Issue 4, pp. 380-8, 1991 (PubMed).

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