CCL7 antibody
Quick Overview for CCL7 antibody (ABIN114716)
Target
See all CCL7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity Chromatography on Protein G.
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Immunogen
- Recombinant human MCP-3 (M.W. 8.5 kDa containing 76 amino acids residues)
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Isotype
- IgG1
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Application Notes
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ELISA. Western Blot: An antibody concentration of 1-4 μg/mL will allow visualization of 0.1 μg/lane of human MCP-3.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with double distillated water to adjust the final concentration to 1.00 mg/mL
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Buffer
- 0.01 M PBS, pH 7.2 without preservatives.
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Preservative
- Without preservative
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Storage
- 4 °C
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Storage Comment
- Store the antibody at 2 - 8 °C. DO NOT FREEZE!
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- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
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Alternative Name
- MCP3 / CCL7
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Background
- MCP3/CCL7 is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7
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Gene ID
- 6354
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NCBI Accession
- NP_006264
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UniProt
- P80098
Target
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