MME antibody

Catalog No. ABIN115280

The Mouse Monoclonal anti-MME antibody is suitable to detect MME in samples from Human. It has been validated for IHC (p) and IHC (fro).

Quick Overview for MME antibody (ABIN115280)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MME antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 56C6

Product Details anti-MME Antibody

Specificity: This antibody is specific to CD10 antigen of 100 kDa, also known as common acute lymphocytic leukemia antigen (CALLA).
Cellular Localization: Cell membrane

Purification: Prediluted

Immunogen: Prokaryotic recombinant protein corresponding to the external domain of the CD10 glycoprotein.

Isotype: IgG1

Application Details

Application Notes: Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM Citrate buffer, pH 6.0 prior to immunostaining. We suggest an incubation period of 30 to 60 minutes at room temperature. Recommended Positive Control: Tonsil
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10 / Neprilysin

Target Type: Chemical

Background: CD10 antigen has been identified on the surface of early lymphoid progenitor cells, immature B cells with in adult bone marrow and germinal center B cells with in lymphoid tissue.Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11

Gene ID: 4311

NCBI Accession: NP_000893

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration