IL-20 antibody

Catalog No. ABIN116425

Product Details anti-IL-20 Antibody

Target: IL-20 (IL20) (Interleukin 20 (IL20))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IL-20 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography.

Immunogen: Highly pure (>98%) recombinant hIL-20

Application Details

Application Notes: Neutralization. ELISA: To detect hIL-20 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hIL-20. Western Blot: To detect hIL-20 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-20 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of > 0.2 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Target Details for IL-20

Target: IL-20 (IL20) (Interleukin 20 (IL20))

Alternative Name: Interleukin-20 / IL20 (IL20 Products)

Synonyms: IL-20 antibody, IL10D antibody, ZCYTO10 antibody, Zcyto10 antibody, IL20 antibody, interleukin 20 antibody, IL20 antibody, Il20 antibody

Background: IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.Synonyms: IL-20, ZCYTO10

Gene ID: 50604

NCBI Accession: NP_061194

UniProt: Q9NYY1

Pathways: Protein targeting to Nucleus