IL-20 antibody
Quick Overview for IL-20 antibody (ABIN116425)
Target
See all IL-20 (IL20) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purification
- Affinity chromatography.
-
Immunogen
- Highly pure (>98%) recombinant hIL-20
-
-
-
-
Application Notes
-
Neutralization. ELISA: To detect hIL-20 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hIL-20. Western Blot: To detect hIL-20 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-20 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Reconstitution
- Restore in sterile water to a concentration of > 0.2 mg/mL.
-
Buffer
- PBS, pH 7.2 without preservatives.
-
Preservative
- Without preservative
-
Handling Advice
- Avoid repeated freezing and thawing.
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
-
-
- IL-20 (IL20) (Interleukin 20 (IL20))
-
Alternative Name
- Interleukin-20 / IL20
-
Background
- IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.Synonyms: IL-20, ZCYTO10
-
Gene ID
- 50604
-
NCBI Accession
- NP_061194
-
UniProt
- Q9NYY1
-
Pathways
- Protein targeting to Nucleus
Target
-