CRNN antibody (AA 259-274)

Catalog No. ABIN1169072

There is 1 publication for this product available. The Rabbit Polyclonal anti-CRNN antibody is suitable to detect CRNN in samples from Human. It has been validated for WB and IHC.

Quick Overview for CRNN antibody (AA 259-274) (ABIN1169072)

Target: CRNN (Cornulin (CRNN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRNN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CRNN Antibody

Binding Specificity: AA 259-274

Purpose: anti-Cornulin (human), pAb (SZ1229)

Specificity: Recognizes human cornulin. Detects a band of ~70 kDa by Western blot.

Characteristics: Polyclonal Antibody. Recognizes human cornulin. Detects a band of ~70 kDa by Western blot. Source: Rabbit. Applications: IHC, WB. Liquid. In PBS containing 1 % BSA and 0.01 % sodium azide. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines. It attenuates deoxycholic acid (DCA)-induced apoptotic cell death and the release of calcium. In overexpressed oral squamous carcinoma cell lines, cornulin negatively regulates cell proliferation by the induction of G1 arrest.

Immunogen: Synthetic peptide corresponding to aa 259-274 (E259ATNDQNRGTETHGQG274) of human cornulin.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In PBS containing 1 % BSA and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze/thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

References for anti-CRNN antibody (ABIN1169072)

Contzler, Favre, Huber, Hohl: "Cornulin, a new member of the "fused gene" family, is expressed during epidermal differentiation." in: The Journal of investigative dermatology, Vol. 124, Issue 5, pp. 990-7, (2005) (PubMed).

Target Details for CRNN

Target: CRNN (Cornulin (CRNN))

Alternative Name: Cornulin

Background:

Alternate Names/Synonyms: Tumor Related Protein, C1orf10 Gene Product, Chromosome 1 Open Reading Frame 10 Gene Product

Product Description: Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines. It attenuates deoxycholic acid (DCA)-induced apoptotic cell death and the release of calcium. In overexpressed oral squamous carcinoma cell lines, cornulin negatively regulates cell proliferation by the induction of G1 arrest.

UniProt: Q9UBG3